Lenti Citations

OriGene产品已被全世界的科学家广泛使用，以提高他们的研究效率。 为了供您参考，我们收集了一些使用OriGene产品发表过的代表性的引用文献，将其发布在此页面上。

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这是研究人员使用OriGene产品后最新发表的一些论文。

靶点 研究论文 杂志 产品类型 货号
A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence G3: Genes|Genomes|Genetics Lenti TR30038
Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling Nature Communications Lenti PS100092V
Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states Nature Communications Lenti PS100093V
ROS-Induced Mitochondrial Dysfunction in CD4 T Cells from ART-Controlled People Living with HIV Viruses Lenti PS100064V
Targeting WDxR motif reprograms immune microenvironment and inhibits hepatocellular carcinoma progression EMBO Molecular Medicine Lenti TR30021V
Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation Cancer immunology research Lenti TR30025
Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation Cancer immunology research Lenti TR30037
Hyperandrogenism diminishes maternal–fetal fatty acid transport by increasing FABP4-mediated placental lipid accumulation Biology of Reproduction Lenti TR30038
Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis Cell Reports Medicine Lenti PS100092V
SHP1 loss augments DLBCL cellular response to ibrutinib: a candidate predictive biomarker. Oncogene Lenti TR30036
Diesel exhaust particle exposure accelerates oxidative DNA damage and cytotoxicity in normal human bronchial epithelial cells through PD-L1. Environmental pollution (Barking, Essex : 1987) Lenti PS100071V
Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10. Cancer letters Lenti PS100093V
Downregulation of AT-rich interaction domain 2 underlies natural killer cell dysfunction in oral squamous cell carcinoma. Immunology and cell biology Lenti TR30037
LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1 Cancer Cell International Lenti TR30036
Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research Lenti PS100092V
High expression levels of FANCI correlate with worse prognosis and promote tumor growth of lung adenocarcinoma partly via suppression of M1 macrophages. Gene Lenti PS100092V
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation Cell reports Lenti TR30021V
Islet primary cilia motility controls insulin secretion Science Advances Lenti TR30021V
MiR-30a-5p and miR-153-3p regulate LPS-induced neuroinflammatory response and neuronal apoptosis by targeting NeuroD1 BMB Reports Lenti TR30036
Hypoxia inhibits the cardiac I K1 current through SUMO targeting Kir2.1 activation by PIP 2 iScience Lenti TR30021V
Chemerin promotes the pathogenesis of preeclampsia by activating CMKLR1/p-Akt/CEBPɑ axis and inducing M1 macrophage polarization. Cell biology and toxicology Lenti TR30036
Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2 Cellular and Molecular Gastroenterology and Hepatology Lenti PS100064V
Neurexin 3α in the Central Amygdala has a Role in Orofacial Varicella Zoster Pain. Neuroscience Lenti TR30021V
A new laser device for ultra-rapid and sustainable aerosol sterilization Environment International Lenti TR30025
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue Cell metabolism Lenti PS100093V
Cocaine-Induced Changes in Sperm Cdkn1a Methylation Are Associated with Cocaine Resistance in Male Offspring. The Journal of neuroscience : the official journal of the Society for Neuroscience Lenti TR30021V
FAM83A is a potential biomarker for breast cancer initiation Biomarker Research Lenti PS100093V
Alzheimer’s vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling Cell reports Lenti TR30037
Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis Cell reports Lenti TR30021V
Peroxiredoxin 5 is involved in cancer cell invasion and tumor growth of oral squamous cell carcinoma. Oral diseases Lenti TR30037
The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma Scientific Reports Lenti PS100064V
Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma International Journal of Oncology Lenti TR30036
A role for alternative splicing in circadian control of exocytosis and glucose homeostasis Genes & Development Lenti PS100092V5
Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause profibrotic changes in linear morphoea fibroblasts. The British journal of dermatology Lenti PS100064V
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells Theranostics Lenti TR30021V
A1CF The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing Cell Rep Lenti MR224176L1
ABAT Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway JCI Insight Lenti TL508059V
ABCA1 ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma Cells Lenti TL315036V
ABCA1 Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment J. Lipid Res. Lenti TL315036
ABCC5 Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer Cancer cell international Lenti TL315024
ABCG1 Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment J. Lipid Res. Lenti TL306915
ACE2 Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike bioRxiv : the preprint server for biology Lenti RC208442L4
ACKR3 Modulation of CXC-motif chemokine receptor 7, but not 4, expression is related to migration of the human prostate cancer cell LNCaP: regulation by androgen and inflammatory stimuli Inflamm. Res. Lenti TL515747
Ackr3 Proinflammatory CXCL12-CXCR4/CXCR7 signaling axis drives Myc-induced prostate cancer in obese mice Cancer Res. Lenti TL515747
ACKR3 ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization J. Cell. Mol. Med. Lenti TL305345
ACKR3 Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration Nat. Cell Biol. Lenti TL305345
Ackr3 Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration Nat. Cell Biol. Lenti TL515747
ACSL1 Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function J. Lipid Res. Lenti TL709438
ACSL4 The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma Aging (Albany NY) 2020 Lenti RC221413L4
ACTR3 Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion J. Cell. Sci. Lenti MR217895L2
ADAM12 A Disintegrin and Metalloprotease 12 Promotes Tumor Progression by Inhibiting Apoptosis in Human Colorectal Cancer Cancers Lenti TL306850
ADAM9 Analysis of ADAM9 Regulation and Function in Vestibular Schwannoma Primary Cells Research Square Lenti TL314947V
ADAMTS8 Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts Br. J. Dermatol. Lenti RC212446L4V
ADAR Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation Nat. Med. Lenti RC207522L1
ADGRG1 GPR56/ADGRG1 is associated with response to antidepressant treatment Nat Commun Lenti MR210044L2V
ADH1B Further evidence supporting a potential role for ADH1B in obesity Scientific reports Lenti RC205391L3
AFDN Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation Nat. Struct. Mol. Biol. Lenti TL311457
AGBL2 AGBL2 promotes cancer cell growth through IRGM-regulated autophagy and enhanced Aurora A activity in hepatocellular carcinoma Cancer Lett.2017 Lenti TL306802
AGER Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells Mol Med Rep Lenti RC204664L2
AGER AGER promotes proliferation and migration in cervical cancer Biosci. Rep. Lenti RC204664L2
Ago2 AGO2 mediates MYC mRNA stability in hepatocellular carcinoma Molecular cancer research : MCR Lenti RR210245L3V
AGO2 AGO2 mediates MYC mRNA stability in hepatocellular carcinoma Mol. Cancer Res. Lenti TL313261
AGO2 AGO2 mediates MYC mRNA stability in hepatocellular carcinoma Mol. Cancer Res. Lenti RC218078L2
AGPAT2 Terapia génica y celular para la corrección de la Lipodistrofia Congénita Generalizada Thesis Lenti TL314894
AHR Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma Nat Commun Lenti TL320259
AHR Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells Nat Commun Lenti TL320259
AIF1 AIF-regulated oxidative phosphorylation supports lung cancer development Cell Res. Lenti TL314878
AIFM1 Overexpression of apoptosis-inducing factor mitochondrion-associated 1 (AIFM1) induces apoptosis by promoting the transcription of caspase3 and DRAM in hepatoma cells Biochem. Biophys. Res. Commun. Lenti TL302572
AIRE The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages Front. Immunol. Lenti RC213497L2
AKT1 MAT1 facilitates the lung metastasis of osteosarcoma through upregulation of AKT1 expression Life Sci. Lenti TL320260
AKT3 Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway Oncotarget Lenti TL320629
ALDH18A1 Global metabolic profiling identifies a pivotal role of proline and hydroxyproline metabolism in supporting hypoxic response in hepatocellular carcinoma Clin. Cancer Res.2017 Lenti TL314847
ALDH1A1 Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells J. Exp. Clin. Cancer Res. Lenti RC200723L1V
Aldh1a3 Concerted Action of Aldehyde Dehydrogenases Influences Depot-Specific Fat Formation Molecular Endocrinology Lenti RR201952L3V
ALDH1L2 Effects of a Lactobacillus fermentation product on the fecal characteristics, fecal microbial populations, immune function, and stress markers of adult dogs. Journal of animal science Lenti TL314843V
ALDH3A1 ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output Cancers (Basel) 2019 Lenti RC202440L1
ALDH3A1 Mutation of the gene encoding the circadian clock component PERIOD2 in oncogenic cells confers chemoresistance by up-regulating the Aldh3a1 gene J. Biol. Chem. Lenti TL510377
ALDH3A1 Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase Cancer Res. Lenti TL510377
ALKBH1 The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation bioRxiv Lenti RR214755L2V
ALOX15 PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function Cell Chem Biol Lenti TL314822
alpha Internexin a-Internexin and Peripherin: Expression, Assembly, Functions, and Roles in Disease Methods in Enzymology Lenti RC202877L2
Amd1 Increased polyamines as protective disease modifiers in Congenital Muscular Dystrophy Hum. Mol. Genet. Lenti RR205647L2
AMELX Effects of full-length human amelogenin on the differentiation of dental epithelial cells and osteoblastic cells Arch. Oral Biol. Lenti RC215582L1
AMFR Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer Elife Lenti TL316441
ANGPTL4 Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes NPJ Precis Oncol Lenti TL317168
ANO1 High level of ANO1 promotes pancreatic cancer growth in concert with oncogenic KRAS. Molecular biology reports Lenti RC213098L4V
ANO1 Suppression of CaMKIIβ Inhibits ANO1-Mediated Glioblastoma Progression Cells Lenti TL300993
ANXA2 Clinical Significance of Annexin A2 Expression in Breast Cancer Patients Cancers Lenti RC205081L4
ANXA2 Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting Sci Rep Lenti TL314772
ANXA2 Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting Scientific Reports Lenti TL314772V
AP2S1 Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity J. Virol. Lenti TL306655
AP2S1 HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system J. Virol. Lenti TL306655
APOE C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease Molecular psychiatry Lenti TL314721
AQP4 Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema Cell Lenti TL709442
AQP4 Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma Nat Commun Lenti RC204693L1
Ar Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression Nature cancer Lenti TL514763V
ARFGAP3 Small-molecule synergist of the Wnt/?-catenin signaling pathway Lenti RC202392L3V
ARHGEF7 ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells Int. J. Oncol. Lenti TL306604
ARHGEF7 ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells Int. J. Oncol. Lenti RC218946L1
Arid2 Downregulation of AT-rich interaction domain 2 underlies natural killer cell dysfunction in oral squamous cell carcinoma. Immunology and cell biology Lenti MR210920L4V
ARID3B ARID3B Directly Regulates Ovarian Cancer Promoting Genes PLoS ONE Lenti RC206328L2
ARIH2 E6AP/UBE3A catalyzes encephalomyocarditis virus 3C protease polyubiquitylation and promotes its concentration reduction in virus-infected cells Biochemical and biophysical research communications Lenti RC201846L1V
ARPC5 Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling Nature Communications Lenti RC212631L3V
ATF4 A Novel Dual Kinase Function of the RET Proto-oncogene Negatively Regulates Activating Transcription Factor 4-Mediated Apoptosis J. Biol. Chem. Lenti RC222709L1
ATG5 Autophagy regulates trophoblast invasion by targeting NF-κB activity Sci Rep Lenti TL314610
ATG5 Basal autophagy is pivotal for Hodgkin and Reed-Sternberg cells' survival and growth revealing a new strategy for Hodgkin lymphoma treatment Oncotarget Lenti TL500113
ATG7 Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype Cell Death Dis Lenti TL504956V
ATM SIRT3, a metabolic target linked to ataxia-telangiectasia mutated (ATM) gene deficiency in diffuse large B-cell lymphoma Scientific reports Lenti TL320267V
ATM ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations Proc. Natl. Acad. Sci. U.S.A. Lenti TL320267
ATP1A1 ATP1A1 Integrates AKT and ERK Signaling via Potential Interaction With Src to Promote Growth and Survival in Glioma Stem Cells Front Oncol Lenti TL314602
ATP1B2 An Immunoaffinity-Based Method for Isolating Ultrapure Adult Astrocytes Based on ATP1B2 Targetting by the ACSA-2 Antibody J. Biol. Chem. Lenti TL500159
Atp2b2 Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease Mol. Psychiatry Lenti TL509635
Atp5f1b Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth Cell Death & Disease Lenti RR201124L3V
Atp7a Knockdown of copper-transporting ATPase 1 (Atp7a) impairs iron flux in fully-differentiated rat (IEC-6) and human (Caco-2) intestinal epithelial cells Metallomics Lenti TL711714
Atr ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations Proc. Natl. Acad. Sci. U.S.A. Lenti TL519184
AURKA Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance Oncogene Lenti TL320538
AVPR2 Sensory primary cilium is a responsive cAMP microdomain in renal epithelia Sci Rep Lenti TL513450
AXL Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1+ cell lines Oncotarget Lenti TL320269
AXL Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression Int J Mol Sci Lenti RC206431L2
B2M Interferon-γ signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes Sci Adv Lenti TL314543V
B2M Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells Nat Commun Lenti TL314543
B2M Human follicular helper T cell promoter connectomes reveal novel genes and regulatory elements at SLE GWAS loci bioRxiv Lenti TL314543
B2M Antiviral signalling in human IPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes BioRxiv Lenti TL314543V
BAP1 Sensitivity of mesothelioma cells to PARP inhibitors is not dependent on BAP1 but is enhanced by temozolomide in cells with high-Schlafen 11and low-MGMT expression J Thorac Oncol Lenti RC200378L4
BCL2 Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells J. Biol. Chem Lenti TL316461
BCL2 Inhibition of Bcl-2 potentiates AZD-2014-induced anti-head and neck squamous cell carcinoma cell activity Biochem. Biophys. Res. Commun. Lenti TL316461
Bdh2 Siderophore-mediated iron trafficking in humans is regulated by iron Journal of molecular medicine (Berlin, Germany) Lenti RR213039L3V
BECN1 Autophagy Induction Results in Enhanced Anoikis-resistance in Models of Peritoneal Disease Mol. Cancer Res. Lenti TL314484
BHLHE40 BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver Elife Lenti RR206868LV
BIRC5 HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s Clin Cancer Res. 2013 Nov 22 Lenti TL315477
BMI1 Lens regeneration using endogenous stem cells with gain of visual function Nature Lenti TL314462
BNIP3 Phosphorylation dependent mitochondrial translocation of Nr4a3 provokes cardiomyocyte death Research Square Lenti TL711845V
BORA Bora downregulation results in radioresistance by promoting repair of double strand breaks PLoS ONE Lenti TL307294
Brd4 Inhibition of BRD4 Attenuates Cardiomyocyte Apoptosis via NF-κB pathway in a Rat Model of Myocardial Infarction Cardiovasc Ther Lenti TL704216
c-Myc MYC Amplification as a Potential Mechanism of Primary Resistance to Crizotinib in ALK-Rearranged Non-Small Cell Lung Cancer: A Brief Report Transl Oncol Lenti RC201611L4
C1ORF115 Systematic functional identification of cancer multi-drug resistance genes Genome Biol. Lenti RC206246L2
Ca3 Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death Sci Rep Lenti TL710299
CAB39L CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis Oncogene Lenti TL314249
CACNA1B Reduced N-Type Ca2+Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis J Am Heart Assoc Lenti TL713159
CACNA1C Primary cilium regulates CaV1.2 expression through Wnt signaling J. Cell. Physiol. April 2014 Lenti TL500242
CACNA1G Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx EBioMedicine Lenti TL305680
CACNA1G Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF EBioMedicine Lenti TL305680
CACNA1H Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx EBioMedicine Lenti TL314243
CACNA1H Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF EBioMedicine Lenti TL314243
CACNA1I Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx EBioMedicine Lenti TL314242
CACNA1I Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF EBioMedicine Lenti TL314242
CACNA2D1 α2δ1 may be a potential marker for cancer stem cell in laryngeal squamous cell carcinoma Cancer Biomark Lenti TL314240
CACNA2D3 Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development J. Neurosci. Lenti TL713428
CACNG4 Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis EBioMedicine Lenti RC205154L3
CACNG4 The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification Commun Biol Lenti RC205154L2
CADM1 MicroRNA-155-3p promotes breast cancer progression through down-regulating CADM1 Onco Targets Ther Lenti TL312210
CADM1 Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-?B Inhibitor A20 and Constitutive NF-?B Signaling PLoS Pathog. Lenti TL312210
CAMKK2 Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening Cell Lenti TL711303
CAPN10 Clinical significance of sHER2‑ECD and calpain‑10 expression in tumor tissues of patients with breast cancer Oncol Rep Lenti TL305662
CASP3 Overexpression of apoptosis-inducing factor mitochondrion-associated 1 (AIFM1) induces apoptosis by promoting the transcription of caspase3 and DRAM in hepatoma cells Biochem. Biophys. Res. Commun. Lenti TL305638
CASR Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor bioRxiv Lenti RC211229L4V
CASR Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension Hypertension Lenti TL709816
CASR Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor J Am Heart Assoc Lenti TL709816
CBX8 Upregulated CBX8 promotes cancer metastasis via the WNK2/MMP2 pathway Molecular Therapy - Oncolytics Lenti RC203417L1
CCDC85B CCDC85B promotes non-small cell lung cancer cell proliferation and invasion Mol. Carcinog. Lenti RC201086L1
CCL2 Improved insulin sensitivity in obese-diabetic mice viachitosan Nanomicelles mediated silencing of pro-inflammatory Adipocytokines Nanomedicine : nanotechnology, biology, and medicine Lenti TL501987
CCL2 MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis Breast Cancer Res. Treat. Lenti TL316716
CCL2 MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis Breast Cancer Research and Treatment Lenti TL316716V
CCL2 Chemokine Signaling Facilitates Early-stage Breast Cancer Survival and Invasion through Fibroblast-dependent Mechanisms Mol. Cancer Res.2017 Lenti TL316716
CCL2 Regulatory T cells ameliorate tissue plasminogen activator-induced brain haemorrhage after stroke Brain Lenti TL501987
CCR2 Chemokine Signaling Facilitates Early-stage Breast Cancer Survival and Invasion through Fibroblast-dependent Mechanisms Mol. Cancer Res.2017 Lenti TL321181
CD180 A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi Emerg Microbes Infect Lenti TL314107
CD274 Salmonella Typhimurium increases functional PD-L1 synergistically with IFNγ in intestinal epithelial cells viaSalmonellaPathogenicity Island-2 Infect. Immun. Lenti TL314098
Cd274 Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression J. Clin. Invest. Lenti MR203953L2
CD274 PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p Oncotarget Lenti TL314098V
CD28 CTLA4-Ig prolongs graft survival specifically in young but not old mice Am. J. Transplant. Lenti MR202454L4V
CD40 A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis Sci Rep Lenti RC201977L1
CD44 Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival Nat Commun Lenti TL314080
CD47 Targeting cluster of differentiation 47 improves the efficacy of anti-cytotoxic T-lymphocyte associated protein 4 treatment via antigen presentation enhancement in pancreatic ductal adenocarcinoma Exp Ther Med Lenti MR204706L1
CD47 Targeting cluster of differentiation 47 improves the efficacy of anti-cytotoxic T-lymphocyte associated protein 4 treatment via antigen presentation enhancement in pancreatic ductal adenocarcinoma Exp Ther Med Lenti TL501123
CD70 Breast cancer stem cells characterized by CD70 expression preferentially metastasize to the lungs Breast Cancer Lenti TL308721
CDC42 shRNA mediated inhibition of Cdc42 gene expression in Calu-6 lung cancer cells bioRxiv Lenti TL305497
CDC7 CDC7-dependent transcriptional regulation of RAD54L is essential for tumorigenicity and radio-resistance of glioblastoma Transl Oncol Lenti TL320578
CDH11 Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma Nat Commun Lenti RC203810L1
CDH11 Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis Int. Immunopharmacol. Lenti RC203810L2
CDH3 DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members Proc. Natl. Acad. Sci. U.S.A. Lenti MR227582L1
CDK1 Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy Sci Transl Med Lenti TL320288
CDK2 Cyclin-Dependent Kinase 2 Promotes Tumor Proliferation and Induces Radio Resistance in Glioblastoma Transl Oncol Lenti TL320291
Cdkn1a Cocaine-Induced Changes in Sperm Cdkn1a Methylation Are Associated with Cocaine Resistance in Male Offspring. The Journal of neuroscience : the official journal of the Society for Neuroscience Lenti RR209648L2V
Cdkn1a Cocaine-Induced Changes in Sperm Cdkn1a Methylation Are Associated with Cocaine Resistance in Male Offspring. The Journal of neuroscience : the official journal of the Society for Neuroscience Lenti TL712469V
CDKN1A TERT and DNMT1 expression predict sensitivity to decitabine in gliomas Neuro-oncology Lenti TL305469
CDKN1A Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy Sci Transl Med Lenti TL305469
CDKN1B Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor Sci Rep Lenti RC201661L1
CDKN2A p16(INK4A) induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1 Mol. Carcinog. Lenti RC220937L2
CDKN2A TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts J. Clin. Invest. Lenti RC220937L1
CDKN2A The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA Binding Protein AUF1 J. Biol. Chem. Lenti RC220937L1
CEACAM6 Biological Functions and Identification of Novel Biomarker Expressed on the Surface of Breast Cancer-Derived Cancer Stem Cells via Proteomic Analysis Mol. Cells Lenti TL314003
CEBPA C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease Molecular psychiatry Lenti TL316491
CEBPA C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease Nat Commun Lenti TL316491
CEBPB C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease Molecular psychiatry Lenti TL320301
CEBPB C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease Nat Commun Lenti TL320301
CES1 Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration American journal of human genetics Lenti TL313972V
CGAS The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps Science signaling Lenti RC212386L4
CGGBP1 CGGBP1 regulates CTCF occupancy at repeats Epigenetics Chromatin Lenti TL313955
CGGBP1 CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats bioRxiv Lenti TL313955
CGGBP1 CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats bioRxiv Lenti RC208653L1
CHCHD2 FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase Cancer Cell Lenti TL317169
CHCHD4 Light-Driven Regeneration of Cone Visual Pigments through a Mechanism Involving RGR Opsin in Müller Glial Cells Neuron Lenti TL305417
CHEK1 Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation J Hematol Oncol Lenti RC225807L4
CHEK2 CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6 BMC Cancer Lenti RC212127L1
CIC Inactivation of Capicua drives cancer metastasis Nat. Genet. Lenti RC215209L2
Cip4 Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery Elife Lenti RC201200L1
CLDN18 Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis J. Clin. Invest. Lenti RC212135L2
CLDN4 Ovarian Tumor Cell Expression of Claudin-4 Reduces Apoptotic Response to Paclitaxel Mol. Cancer Res. Lenti RC200490L2
CLTC Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts J. Cell Biol. Lenti TL516542
CLTRN CLTRN, regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathway International journal of radiation oncology, biology, physics Lenti RC204775L2
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COL3A1 COL3A1 Overexpression Associates with Poor Prognosis and Cisplatin Resistance in Lung Cancer Balkan medical journal Lenti TL313797V
Collagen III COL3A1 Overexpression Associates with Poor Prognosis and Cisplatin Resistance in Lung Cancer Balkan medical journal Lenti RC211766L3V
Control Particle The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer Breast cancer research : BCR Lenti TR30021V
Control Particle A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo Cancer Cell Lenti PS100092V
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Control Particles Epigenetic reprogramming of tumor cell-intrinsic STING function sculpts antigenicity and T cell recognition of melanoma Proceedings of the National Academy of Sciences of the United States of America Lenti TR30021V
Control Particles The Small G-Protein RalA Promotes Progression and Metastasis of Triple Negative Breast Cancer Research Square Lenti TR30021V
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Control Particles CLTRN, regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathway International journal of radiation oncology, biology, physics Lenti PS100071V
Control Particles Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism Molecular Therapy - Oncolytics Lenti PS100064V
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CPSF1 Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing PLoS ONE Lenti RC203519L4
CRADD RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production Cell. Physiol. Biochem. Lenti TL319843
Creb3l1 CREB3L1-mediated functional and structural adaptation of the secretory pathway in hormone-stimulated thyroid cells J. Cell. Sci.2017 Lenti TL700673
CREBBP Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence Mol. Cell Lenti RC219036L1
CRHR1 Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology J. Leukoc. Biol. Lenti RC226816L2
CRLF3 Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis Cell reports Lenti TL305215V
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CTNNB1 Secreted phosphoprotein-1 accelerates the progression of human colorectal cancer through activating β-catenin signaling Oncology letters Lenti TL313664
CTNNB1 MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism Cancer cell Lenti TL500280
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CUX1 Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development JCI Insight Lenti RC224512L3V
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CXCL1 Plac1 Is a Key Regulator of the Inflammatory Response and Immune Tolerance In Mammary Tumorigenesis Sci Rep Lenti MR220966L1
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CXCR4 Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment Breast Cancer Research : BCR Lenti TL313630V
CXCR4 CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer Cell death & disease Lenti TL313630
CXCR4 PECAM1 Combines With CXCR4 to Trigger Inflammatory Cell Infiltration and Pulpitis Progression Through Activating the NF-κB Signaling Pathway Frontiers in Cell and Developmental Biology Lenti TL710583V
CXCR4 m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade Nat Commun Lenti RC214548L2
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CXCR4 Proinflammatory CXCL12-CXCR4/CXCR7 signaling axis drives Myc-induced prostate cancer in obese mice Cancer Res. Lenti TL500383
CYBB NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation. International journal of molecular sciences Lenti TL313616V
Cyp11a1 Resveratrol Stimulates Cortisol Biosynthesis by Activating SIRT-Dependent Deacetylation of P450scc Endocrinology Lenti RR210753L3V
CYP1B1 Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation Oncotarget Lenti TL313605
Cyp2j4 Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers Protein Science : A Publication of the Protein Society Lenti RR215375L3V
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DCLK1 Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells Cells Lenti RC217050L2
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DDR2 Targeting DDR2 in head and neck squamous cell carcinoma with dasatinib Int. J. Cancer Lenti TL320440
DDX41 R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability Research Square Lenti TL305064
DDX58 RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway OncoTargets and therapy Lenti MR226477L4V
DEPDC5 Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis Neurobiol. Dis. Lenti TL508165
DHX32 DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the β-catenin pathway Research Square Lenti RC209736L3V
DKK1 Wnt signaling modulator DKK1 as an immunotherapeutic target in ovarian cancer Gynecol. Oncol. Lenti MR203629L3
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DLG2 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma Cell Rep Lenti RC227175L4
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DLL3 Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer EBioMedicine Lenti RC200005L2V
DNAI1 Islet primary cilia motility controls insulin secretion Science Advances Lenti TL313431V
DNAJB1 FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1 Nature Communications Lenti TL313427
DNM2 Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion J. Cell. Sci. Lenti RC223585L2
DNMT1 Targeted phosphoproteomics of the Ras signaling network reveal regulatory mechanisms mediated by oncogenic KRAS bioRxiv Lenti RC226414L1
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DNMT1 Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma Cancer Res. Lenti TL313404
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DOT1L Targeting histone methyltransferase DOT1L by a novel psammaplin A analog inhibits growth and metastasis of triple-negative breast cancer Molecular Therapy - Oncolytics Lenti RC218547L2
DPYSL3 Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium‑mediated cell signaling Oncology Reports Lenti TL313373V
DPYSL3 Collapsin response mediator protein 4 enhances radio-sensitivity through calcium-mediated cell signaling Research Square Lenti TL313373V
DRAM1 Overexpression of apoptosis-inducing factor mitochondrion-associated 1 (AIFM1) induces apoptosis by promoting the transcription of caspase3 and DRAM in hepatoma cells Biochem. Biophys. Res. Commun. Lenti TL307117
DRD2 Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D2 receptor-dependent, manner Pharmacology research & perspectives Lenti RC202476L3V
DRD2 The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells Pharmacology Lenti RC213065L3V
DRD2 Role of Dopamine Receptors in the Anticancer Activity of ONC201 Neoplasia Lenti TL304907
DSCAM Origins and Proliferative States of Human Oligodendrocyte Precursor Cells Cell Lenti TL304905V
DSP Changes in mRNA/protein expression and signaling pathways in in vivo passaged mouse ovarian cancer cells PLoS ONE Lenti TL519230
Dusp16 miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7 Cell Death & Disease Lenti MR209843L3V
DUSP23 Profiling analysis of protein tyrosine phosphatases during neuronal differentiation Neurosci. Lett. Lenti TL317251
DUSP5 Dual specificity phosphatase 5 regulates perfusion recovery in experimental peripheral artery disease Vasc Med Lenti TL518256
E2F1 Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma Cell Rep Lenti RC208247L2
E2F3 Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis Cell Cycle Lenti RC222471L1V
EBF2 Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing Nature Lenti MR224591L3
EDEM2 Innate sensing of influenza A virus hemagglutinin glycoproteins by the host endoplasmic reticulum (ER) stress pathway triggers a potent antiviral response via ER-associated protein degradation J. Virol. Lenti TL304849
EFEMP1 The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion Oncotarget Lenti TL313284
EGFL7 Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion Hum. Gene Ther. Lenti TL508528
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EGR1 Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells Haematologica Lenti TL313277
Eid3 Mesenchymal stem cell-derived extracellular vesicles subvert Th17 cells by destabilizing RORγt through posttranslational modification Experimental & Molecular Medicine Lenti TL703753V
Eid3 Mesenchymal stem cell-derived extracellular vesicles subvert Th17 cells by destabilizing RORγt through posttranslational modification Experimental & Molecular Medicine Lenti RR201693L3V
EIF2S1 Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis Redox Biology Lenti RC200368L3V
Eif3b A threonyl-tRNA synthetase-mediated translation initiation machinery Nature Communications Lenti RR211383L3V
EIF3F Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F Oncogene Lenti RC201740L3
EIF4E Activation of Tyrosine Metabolism in CD13+ Cancer Stem Cells Drives Relapse in Hepatocellular Carcinoma Cancer Res Treat Lenti TL313244
ELOVL2 ELOVL2: a novel tumor suppressor attenuating tamoxifen resistance in breast cancer American Journal of Cancer Research Lenti RC209232L4V
EMSY EMSY expression affects multiple components of skin barrier with relevance to atopic dermatitis Journal of Allergy and Clinical Immunology Lenti RC216916L4
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ENTPD3 Silencing NTPDase3 activity rehabilitates the osteogenic commitment of post-menopausal stem cell bone progenitors Stem Cell Research & Therapy Lenti TL313202V
ENTPD3 Purines 2018 Basic and Translational Science on Purinergic Signaling and its Components for a Healthy and Better World Purinergic Signalling Lenti TL313202V
EP300 Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence Mol. Cell Lenti RC223265L1
EPAS1 miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma Nat Metab Lenti TL315484
EPB41L3 FOXA1 O-GlcNAcylation–mediated transcriptional switch governs metastasis capacity in breast cancer Science Advances Lenti TL313194V
EPGN Regulation of Collective Metastasis by Nanolumenal Signaling Cell Lenti RC214501L4
EPGN Regulation of Collective Metastasis by Nanolumenal Signaling Cell Lenti MR219218L4
ERBB2 Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Herpes Simplex Oncolytic Virus Cancers Lenti RC212583L1V
ERBB2 Tuning the Antigen Density Requirement for CAR T Cell Activity Cancer Discov Lenti RC212583L1
ERBB2 The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival Theranostics Lenti TL709823
ERBB2 Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications Chembiochem Lenti TL320342
ERBB2 Transmembrane Domain Targeting Peptide Antagonizing ErbB2/Neu Inhibits Breast Tumor Growth and Metastasis Cell Rep Lenti TL320342
ERBB3 ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma. Cell reports Lenti TL320343V
ERCC2 ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer Clin. Cancer Res. Lenti RC215058L1
ERCC2 XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage Nucleic Acids Res. Lenti TL313180
ERCC4 A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance Cancer Res. Lenti RC223300L1
ERCC6 Elevated Expression of ERCC6 Confers Resistance to 5-Fluorouracil and Is Associated with Poor Patient Survival in Colorectal Cancer DNA Cell Biol. Lenti TL313176
ERVW-1 Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer Viruses Lenti RC213951L1V
ESR1 17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation Biosci. Rep. Lenti TL510613
Esr1 Modulation effects of black-vinegar based supplement against a high-fat dietary habit: antiobesity/hypolipidemic, antioxidative, and energy-metabolism effects J. Sci. Food Agric. Lenti TL510613
ESR1 Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration Theranostics Lenti RC213277L2
ESR1 PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells BMC Cancer Lenti TL320346
ESR2 Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration Theranostics Lenti RC218519L2
ESRRA NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk J. Neurosci. Lenti MR225753L1
ESRRA NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk J. Neurosci. Lenti TL502583
ETS1 ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes Front Oncol Lenti RC215203L2
ETS1 ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes Front Oncol Lenti TL313153
EZH2 A non-canonical function of Ezh2 preserves immune homeostasis EMBO Rep Lenti RC202054L1
EZH2 Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma Biochem. Biophys. Res. Commun. Lenti TL304713
EZH2 Sunitinib dose-escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modifications Mol. Cancer Ther. Lenti TL304713
FAM50B Combinatorial CRISPR screen identifies fitness effects of gene paralogues Nature communications Lenti RC201531L3
FANCI High expression levels of FANCI correlate with worse prognosis and promote tumor growth of lung adenocarcinoma partly via suppression of M1 macrophages. Gene Lenti RC218972L3V
FANCI CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI Cell Death Discov Lenti RC226384L4
FASN Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice Scientific Reports Lenti TL313058V
FBL Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells Cancer Cell Lenti TL313054
FBLN2 Correlation of Fibulin-2 expression with proliferation, migration and invasion of breast cancer cells Oncology Letters Lenti RC218622L3V
FBLN2 Correlation of Fibulin‑2 expression with proliferation, migration and invasion of breast cancer cells Oncol Lett Lenti RC218622L3
FBXW7 F-Box/WD Repeat Domain-Containing 7 Induces Chemotherapy Resistance in Colorectal Cancer Stem Cells Cancers (Basel) 2019 Lenti TL304541
FCGR1A Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression Nature Biotechnology Lenti RC207487L2V
FERMT2 The focal adhesion protein kindlin-2 controls mitotic spindle assembly by inhibiting histone deacetylase 6 and maintaining α-tubulin acetylation J. Biol. Chem. Lenti TL310359
FFAR4 Different effects of G-protein-coupled receptor 120 (GPR120) and GPR40 on cell motile activity of highly migratory osteosarcoma cells. Biochemical and biophysical research communications Lenti TL307824V
FFAR4 Different effects of GPR120 and GPR40 on cellular functions stimulated by 12-O-tetradecanoylphorbol-13-acetate in melanoma cells. Biochemical and biophysical research communications Lenti TL307824V
Ffar4 Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor. Biochemical and biophysical research communications Lenti RR202773L3V
Fgf15 A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion Cell Rep Lenti TL514099
FGFR3 ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma. Cell reports Lenti TL320355V
FGFR3 Modulation of HCV reinfection after orthotopic liver transplantation by fibroblast growth factor-2 and other non-interferon mediators Gut Lenti RC215533L2
FLT1 Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration Cell Rep Lenti RC224406L2
FLT3 Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34+ Hematopoietic Progenitor Cells from Apoptosis mSphere Lenti RC211459L4V
FMR1 Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge Oncogene Lenti TL312955
FN1 Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis Onco Targets Ther Lenti TL304489
Folate Binding Protein Modification of cytokine-induced killer cells with folate receptor alpha (FRα)-specific chimeric antigen receptors enhances their antitumor immunity toward FRα-positive ovarian cancers Mol. Immunol. Lenti RC221050L1
FOLR1 Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer Clin. Cancer Res. Lenti TL304479
FOLR2 Targeting of folate receptor-beta on acute myeloid leukemia blasts with chimeric antigen receptor expressing T cells Blood Lenti RC212993L1
FOS Nkx6.1-mediated insulin secretion and ß-cell proliferation is dependent on upregulation of c-Fos FEBS Lett. Lenti TL710577
FOSL1 The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS-like antigen 1 Mol. Carcinog. Lenti RC202104L2
FOXA1 FOXA1 O-GlcNAcylation–mediated transcriptional switch governs metastasis capacity in breast cancer Science Advances Lenti TL312942V
FOXA3 Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration Theranostics Lenti RC202363L2
FOXC1 Oct4-dependent FoxC1 Activation Improves the Survival and Neovascularization of Mesenchymal Stem Cells under Myocardial Ischemia Research Square Lenti TL513221V
FOXD3 Activation of Tyrosine Metabolism in CD13+ Cancer Stem Cells Drives Relapse in Hepatocellular Carcinoma Cancer Res Treat Lenti TL312939
FOXF1 Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett’s like metaplasia Laboratory investigation; a journal of technical methods and pathology Lenti TL312936V
FOXF1 Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett\'s like metaplasia Laboratory investigation; a journal of technical methods and pathology Lenti RC218259L2V
FOXO3 Mitochondrial FOXO3a is involved in amyloid ß peptide-induced mitochondrial dysfunction J. Bioenerg. Biomembr. Lenti TL704976
FSCN1 Fascin is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway Stem Cells Lenti TL312916
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FTO FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell bioRxiv Lenti TL308064
FTO The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells Cancer Cell Int. Lenti TL308064
FTO R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling Cell Lenti TL308064
FTO Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication J. Virol. Lenti TL308064
FTO FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase Cancer Cell Lenti TL308064
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FZD5 ARID3B Directly Regulates Ovarian Cancer Promoting Genes PLoS ONE Lenti RC213960L2
GAB2 Gab2 Ablation Reverses the Stemness of HER2-Overexpressing Breast Cancer Cells Cell. Physiol. Biochem. Lenti TL312875
GABRG2 Shifting hippocampal excitation/inhibition balance modifies despair-like behavior in mice bioRxiv Lenti TL515175
GABRG2 Hippocampal GABA-inhibitory circuitry regulates despair-like behavior in mice bioRxiv Lenti TL515175
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GATA1 The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production J. Immunol. Lenti TL500772
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GBP5 Guanylate Binding Protein 5 (GBP5) regulates synovial fibroblast mediated inflammation and tissue destruction in rheumatoid arthritis Arthritis & Rheumatology Lenti RC225986L2V
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GCK Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation Nat Metab Lenti RC200472L1
GDF15 Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture Glia Lenti TL710232
Gfpt1 Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer Cell Death Dis Lenti TL511601V
GFPT1 Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway Oncogenesis Lenti TL511601
GLUL Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma Nat. Cell Biol. Lenti TL312740
GMNN Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors Development Lenti TL304304
GOLPH3 Lentivirus Mediated GOLPH3 shRNA Inhibits Growth and Metastasis of Esophageal Squamous Cancer Asian Pac. J. Cancer Prev. 5391-6 Lenti TL317415
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GPRC5A Orphan G protein-coupled receptor GPRC5A modulates integrin ß1-mediated epithelial cell adhesion Cell Adh Migr Lenti RC200118L1
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GRHL2 Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways Oncogenesis Lenti TL304206
GRIN2B Synaptic proximity enables NMDAR signalling to promote brain metastasis Nature Lenti RC223623L2
GRK5 GRK5 is an Essential Co-repressor for Cardiac Mineralocorticoid Receptor Antagonism induced by Finerenone but not Eplerenone preprints Lenti RC209137L4V
GRSF1 Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program Nucleic Acids Res. Lenti TL312593
GRSF1 GRSF1 suppresses cell senescence Aging (Albany NY) 2018 Lenti TL312593V
GSTA2 Glutathione S-transferase A2 (GSTA2) Promotes Hepatocellular Carcinoma Recurrence After Liver Transplantation Through Modulating Reactive Oxygen Species Metabolism Research Square Lenti RC202479L2
Gucy1a1 Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells Cell. Signal. Lenti MR210068L1
GUCY2C A Novel GUCY2C-CD3 T cell Engaging Bispecific construct (PF-07062119) for the Treatment of Gastrointestinal Cancers Clin. Cancer Res. Lenti RC213901L3
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H19 Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma Biochem. Biophys. Res. Commun. Lenti TL318197
HADHA Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas The Journal of clinical investigation Lenti TL312528V
HAT1 HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding Molecular Cell Lenti RC209571L1
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Havcr1 Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site. Molecular and cellular biochemistry Lenti MR203831L3V
HAVCR1 Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma Scientific reports Lenti MR203831L3V
HAVCR1 Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation PloS one Lenti MR203831L3
HBP1 UHRF1 regulates the transcriptional repressor HBP1 through MIF in T acute lymphoblastic leukemia Oncology reports Lenti TL312507
HBP1 ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the , MIF Immune Susceptibility Locus Arthritis & rheumatology (Hoboken, N.J.) 2021 Lenti TL312507
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Hcar1 Cell surface lactate receptor GPR81 is crucial for cancer cell survival Cancer research Lenti MR225816L3V
HCK DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies. Cells Lenti RC217022L4V
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HDAC4 HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder Hum. Mol. Genet. Lenti TL510852
HDAC6 Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity Blood Adv Lenti RC209649L4V
HDGF A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease Sci Rep Lenti RC204148L1
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HEY2 Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis Nature Communications Lenti RC202544L2V
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HGF New Paradigms to Assess Consequences of Long-Term, Low-Dose Curcumin Exposure in Lung Cancer Cells Molecules Lenti TL312467
HIF1A Sulforaphane Inhibits Nonmuscle Invasive Bladder Cancer Cells Proliferation through Suppression of HIF-1α-Mediated Glycolysis in Hypoxia J. Agric. Food Chem. Lenti TL320380
HIF1A miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma Nat Metab Lenti TL320380
HIF1A A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2 J Biol Eng Lenti TL320380
HIF1A Activation of EGFR/p38/HIF-1a is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium J. Biol. Chem. Lenti TL320380
HIF1A Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells Biochim. Biophys. Acta Lenti TL320380
HIPK1 Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells Nat Commun Lenti TL320769
HIPK1 Human follicular helper T cell promoter connectomes reveal novel genes and regulatory elements at SLE GWAS loci bioRxiv Lenti TL320769
HMGB1 High mobility group box 1 promotes sorafenib resistance in HepG2 cells and in vivo BMC Cancer Lenti RC205918L2
HMGCR Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC) J. Biol. Chem. Lenti TL312393
Hmgn3 High mobility group nucleosome-binding family proteins promote astrocyte differentiation of neural precursor cells. Stem cells (Dayton, Ohio) Lenti MR200264L3V
HMOX1 Synthetically Lethal Interactions of Heme Oxygenase-1 and Fumarate Hydratase Genes Biomolecules Lenti TL312388
HMOX1 Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo Mediators of Inflammation Lenti TL500966
Hmox1 Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinases- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis Infect. Immun. Lenti MR203944L1
HNF1A Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells Nature communications Lenti RC211201L2
HNF1A Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration Theranostics Lenti RC211201L2
HNF1A Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance Cancer Cell Lenti RC211201L1
HNF4 gamma miR-34a Inhibits Proliferation and Invasion of Bladder Cancer Cells by Targeting Orphan Nuclear Receptor HNF4G Disease Markers Lenti RC219703L2
HNF4A Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration Theranostics Lenti RC217863L2
Hnf4a Hepatocyte Nuclear Factor-4 alpha in Noise-Induced Cochlear Neuropathy Dev Neurobiol Lenti TL500970
HNRNPA1 Genome-wide analysis of pseudogenes reveals HBBP1\'s human-specific essentiality in erythropoiesis and implication in β-thalassemia Developmental cell Lenti TL312381
HNRNPA2B1 Prion-like domain mutations in hnRNPs cause multisystem proteinopathy and ALS Nature Lenti RC224241L1V
HNRNPD The inflammatory/cancer-related IL-6/STAT3/NF-?B positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts Oncotarget Lenti RC201796L2
HNRNPD The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA Binding Protein AUF1 J. Biol. Chem. Lenti RC201796L1
HOXA13 CDH17 is a downstream effector of HOXA13 in modulating the Wnt/β-catenin signaling pathway in gastric cancer Eur Rev Med Pharmacol Sci Lenti RC209698L1
HOXA9 Analysis of HOX gene expression and the effects of HOXA9 overexpression in fibroblasts derived from keloid lesions and normal skin Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society Lenti RC200559L2V
HOXB9 A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer Nat Commun Lenti RC213735L2
HOXC13 Transcriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13 Genesis Lenti TL304059
HOXC4 MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis Frontiers in Cell and Developmental Biology Lenti TL304058V
HOXD10 Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma J. Cell. Biochem. Lenti RC210208L3
HPSE Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop Oncotarget Lenti TL307138
HSF1 C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease Molecular psychiatry Lenti TL312318
HSF1 C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease Nat Commun Lenti TL312318
HSPA5 ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness" Cell Death Dis Lenti TL312303
HSPA5 ER translocation of the MAPK pathway drives therapy resistance in BRAF mutant melanoma Cancer Discov Lenti TL500881
HSPA5 Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca2+-signaling Sci Rep Lenti TL312303
HSPA6 Heat Shock Protein 70B? (HSP70B?) Expression and Release in Response to Human Oxidized Low Density Lipoprotein Immune Complexes in Macrophages The Journal of Biological Chemistry Lenti RC207795L3V
HSPA9 HSPA9/Mortalin Mediates Axo-Protection by Modulating Mitochondrial Dynamics in Neurons Research Square Lenti TL704140
HSPB2 Schisandrin B ameliorates high glucose-induced vascular endothelial cells injury by regulating Noxa/Hsp27/NF-κB signaling pathway Biochem. Cell Biol. Lenti TL312300
HYAL4 A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Bladder Cancer Patients Clin. Cancer Res. Lenti TL312276
ICAM1 CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin Cell Host & Microbe Lenti MR227081L4
ICAM1 Cell-specific targeting by Clostridium perfringens β-toxin unraveled: the role of CD31 as the toxin receptor bioRxiv Lenti RC200714L3
ICAM5 ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68 Cell Host & Microbe Lenti TL312266
ICOSLG Non-immune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist J. Clin. Invest. Lenti RC208975L2
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IDO1 Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer Mol. Cancer Res. Lenti TL312147
IDO1 Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation Cancer Cell Lenti TL511273
IDO1 Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells Nat Commun Lenti RC206592L1
IDO1 Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells Nat Commun Lenti TL312147
IFIH1 ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity Nature microbiology Lenti TL303992V
Ift88 IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Human genetics Lenti RR202624L3V
IGF1R Pharmacological Inhibition of Insulin Growth Factor-1 Receptor (IGF-1R) Alone or in Combination With Ruxolitinib Shows Therapeutic Efficacy in Preclinical Myeloproliferative Neoplasm Models HemaSphere Lenti TL320384
Igf1r The insulin-like growth factor I receptor regulates glucose transport by astrocytes Glia Lenti TL501056
Igfbp2 Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis Cell Reports Medicine Lenti MR204287L3V
IGFBP2 IGFBP2 protects against pulmonary fibrosis through inhibiting P21-mediated senescence bioRxiv Lenti MR204287L3V
IKZF1 Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2 International journal of molecular sciences Lenti TL308127
IKZF1 Welcome to the 10th volume of Epigenomics. Epigenomics Lenti TL308127V
Il1f9 IL-36 receptor promotes resolution of intestinal damage Journal of immunology (Baltimore, Md. : 1950) Lenti MR219429L3V
Il27 Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival J Immunother Cancer Lenti TL507534
IL37 Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice Proc. Natl. Acad. Sci. U.S.A Lenti TL303957
IL6 Antitumor and Anti-Invasive Effect of Apigenin on Human Breast Carcinoma through Suppression of IL-6 Expression Int J Mol Sci Lenti TL312162
IL6 Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model Med. Sci. Monit. Lenti MR227281L2
IL6R Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells Leukemia Lenti TL312161
Impdh2 Overexpression of Inosine 5′-Monophosphate Dehydrogenase Type II Mediates Chemoresistance to Human Osteosarcoma Cells PLoS ONE Lenti RR209085L3V
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INPP4B INPP4B exerts a dual function in the stemness of colorectal cancer stem-like cells through regulating Sox2 and Nanog expression Carcinogenesis Lenti TL312138
Insr The insulin-like growth factor I receptor regulates glucose transport by astrocytes Glia Lenti TL501102
IRS4 Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking Nat. Genet. Lenti RC218385L1
ISG15 ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity Nature microbiology Lenti TL319471V
ITGA2 CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression Oncotarget Lenti RC212617L1
ITGA5 O-GlcNAcylation of ITGA5 facilitates the occurrence and development of colorectal cancer Exp. Cell Res. Lenti TL312094
ITGAM Microglial complement receptor 3 regulates brain Aß levels through secreted proteolytic activity J. Exp. Med Lenti TL501116
ITGB5 αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors Brain Res. Lenti TL516440
ITGB5 αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors Brain Res. Lenti MR222893L1
JAK1 IGHG1 functions as an oncogene in tongue squamous cell carcinoma via JAK1/STAT5 signaling European Review for Medical and Pharmacological Sciences Lenti TL320394
JARID2 Jarid2 enhances the progression of bladder cancer through regulating PTEN/AKT signaling Life Sci. Lenti TL312055
JMJD6 Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness properties Carcinogenesis Lenti TL310083
JPH3 Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability Cell Rep Lenti TL705996
JPH4 Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability Cell Rep Lenti TL700489
KAT8 Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment Nucleic Acids Res. Lenti TL303060
Kcnj2 Hypoxia inhibits the cardiac I K1 current through SUMO targeting Kir2.1 activation by PIP 2 iScience Lenti TL710087V
KCNK2 Trabecular Meshwork TREK-1 Channels Function as Polymodal Integrators of Pressure and pH Invest. Ophthalmol. Vis. Sci. Lenti TL312003
KCNQ1 Suppression-Replacement KCNQ1 Gene Therapy for Type 1 Long QT Syndrome Circulation Lenti TL303806
KCTD5 K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca2+ Signaling and Rac1 Activity Cells Lenti TL303786
KDM3A Hypoxia-inducible KDM3A addiction in multiple myeloma Blood Adv Lenti TL303857
KDM4B Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells Stem Cell Reports Lenti RC223401L3
KDM4B Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells Stem Cell Reports Lenti TL312052
KDM5A Vitamin C promotes pluripotency of human induced pluripotent stem cells via the histone demethylase JARID1A Biol. Chem. Lenti TL312057
KDM6A Contingencies of UTX/KDM6A Action in Urothelial Carcinoma Cancers (Basel) 2019 Lenti RC210861L2
KDM6A MBD3/NuRD loss participates with KDM6A program to promote DOCK5/8 expression and Rac GTPase activation in human acute myeloid leukemia FASEB J. Lenti RC210861L4
KDM6A THE ROLE OF KDM6A/UTX IN BLADDER CANCER: FROM MUTATIONS TO THERAPEUTIC INTERVENTION thesis Lenti RC210861L2
KDM6B Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase Oncogenesis Lenti TL320873
KDM6B Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B J. Clin. Invest. Lenti HC141378
KDSR Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia Haematologica Lenti RC201153L3
KEAP1 Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells Theranostics Lenti RC202189L4
Khk A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes STAR Protocols Lenti MR204149L2V
KHSRP KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression Nat Commun Lenti TL311984
KIF13A KIF13A mediates the activity-dependent transport of ESCRT-0 proteins in axons bioRxiv Lenti TL706020
KIF18A Expression of KIF18A Is Associated with Increased Tumor Stage and Cell Proliferation in Prostate Cancer Med. Sci. Monit. Lenti TL303697
KIF26B Upregulation of KIF26B, Cell Migration and Proliferation of Human Ovarian Cancer Cell Lines In Vitro, and Patient Outcomes from Human Bioinformatic Analysis Med. Sci. Monit. Lenti TL508079
KIF3B Identification of kinesin family member 3B (KIF3B) as a molecular target for gastric cancer Kaohsiung J. Med. Sci. Lenti TL311910
KIR2DL5B KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth Oncotarget Lenti RC213765L2
KITLG A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer Cell Death Dis Lenti RC213540L4
KL FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling Cell death & disease Lenti TL303679
KL Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer\'s disease Aging Cell Lenti MR227101L2
KL Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer\'s disease Aging Cell Lenti TL303679
KL Lentiviral vector–mediated overexpression of Klotho in the brain improves Alzheimer's disease–like pathology and cognitive deficits in mice Neurobiology of Aging Lenti MR227101L2
KL Ginsenoside-Rg1 Protects against Renal Fibrosis by Regulating the Klotho/TGF-β1/Smad Signaling Pathway in Rats with Obstructive Nephropathy Biol. Pharm. Bull. Lenti TL711301
KL Lentiviral-mediated klotho up-regulation improves aging-related memory deficits and oxidative stress in senescence-accelerated mouse prone-8 mice Life Sci. Lenti MR227101L2
Kl Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling Front Pharmacol Lenti MR227101L2
Kl Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling Front Pharmacol Lenti TL711301
KLB Klotho Exerts an Emerging Role in Cytokinesis Genes (Basel) 2020 Lenti TL303678
KLF2 Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis J. Clin. Invest. Lenti RC210042L1
KLF3 Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182 Cancer Lett. Lenti TL303669
KLF4 JAK2 inhibition in JAK2V617F-bearing leukemia cells enriches CD34+ leukemic stem cells that are abolished by the telomerase inhibitor GRN163L Biochem. Biophys. Res. Commun. Lenti TL316853
KLF4 TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment Cell Stem Cell Lenti TL316853
KLF4 Kruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele JCI Insight Lenti TL316853
KMT2A Targeting the MLL complex in castration-resistant prostate cancer Nat. Med. Lenti TL311462
KMT2B Targeting the MLL complex in castration-resistant prostate cancer Nat. Med. Lenti TL315696
KNSTRN Characterization of SKAP/Kinastrin isoforms - The N-terminus defines tissue specificity and Pontin binding Hum. Mol. Genet. Lenti TL306156
KTI12 Same but different - Molecular comparison of human KTI12 and PSTK Biochimica et biophysica acta. Molecular cell research Lenti RC204261L3
LAMC2 Exosomal microRNA‑146a derived from mesenchymal stem cells increases the sensitivity of ovarian cancer cells to docetaxel and taxane via a LAMC2‑mediated PI3K/Akt axis Int J Mol Med Lenti RC222076L4
LAMC2 LAMC2 regulated by microRNA-125a-5p accelerates the progression of ovarian cancer via activating p38 MAPK signalling Life Sci. Lenti RC222076L4
LAMP1 Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1 Cell Death Dis Lenti TL311795
LARS1 PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase Nat Commun Lenti RC221682L3
LC3B Curcumin induces apoptotic cell death and protective autophagy by inhibiting AKT/mTOR/p70S6K pathway in human ovarian cancer cells Arch. Gynecol. Obstet. Lenti RC207356L3
LDHA Sirtuin 6 suppresses hypoxia-induced inflammatory response in human osteoblasts via inhibition of reactive oxygen species production and glycolysis-A therapeutic implication in inflammatory bone resorption Biofactors Lenti TL311769
LDLR Targeting lipid droplet lysophosphatidylcholine for cisplatin chemotherapy J. Cell. Mol. Med. Lenti RC200006L2
LDLR Low-Density Lipoprotein Receptor-Mediated Lipidome-Transcriptome Reprogramming Impulses to Cisplatin Insensitivity bioRxiv Lenti RC200006L2
LEF1 Single-cell Analysis Reveals a Preexisting Drug-Resistant Subpopulation in the Luminal Breast Cancer Subtype Cancer Res. Lenti RC208663L1
LEF1 BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells Sci Rep Lenti RC225565L2
Lenti Concentrator Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication Nature immunology Lenti TR30026
Lenti Concentrator EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics EMBO reports Lenti TR30025
Lenti Concentrator Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes Genome Res. Lenti TR30025
Lenti Concentrator Establishment of an induced pluripotent cell line from Taiwan black silkie chick embryonic fibroblasts for replication-incompetent virus production Sci Rep Lenti TR30025
Lenti Concentrator Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-End Tracking Protein Network in Adipocytes Mol. Cell Proteomics Lenti TR30025
Lenti Concentrator The mitochondrial metabolic function of DJ-1 is modulated by 14-3-3β FASEB J. Lenti TR30025
Lenti Titer Kit RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43 Neuron Lenti TR30038
Lenti-vpak Lentiviral Packaging Kit The role of TNFRSF11B in development of osteoarthritic cartilage Rheumatology (Oxford, England) 2021 Lenti TR30037
Lenti-vpak packaging Genome-wide RNAi Screen identifies PMPCB as a therapeutic vulnerability in EpCAM+ hepatocellular carcinoma Cancer Res. Lenti TR30037
Lenti-vpak packaging Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer Oncogene Lenti TR30037
Lenti-vpak packaging The impact of hepatic HSP72 on insulin signaling Am. J. Physiol. Endocrinol. Metab. Lenti TR30037
Lenti-vpak packaging Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma Oncotarget Lenti TR30037P5
Lenti-vpak packaging Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain Dev. Neurosci. Lenti TR30037
Lenti-vpak packaging Targeting LRH‑1 in hepatoblastoma cell lines causes decreased proliferation Oncol. Rep. Lenti TR30037
Lenti-vpak packaging Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model Med. Sci. Monit. Lenti TR30037
Lenti-vpak packaging Wnt5a/FZD4 Mediates the Mechanical Stretch-Induced Osteogenic Differentiation of Bone Mesenchymal Stem Cells Cell. Physiol. Biochem. Lenti TR30037
Lenti-vpak packaging CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation PLoS Pathog. Lenti TR30037
Lenti-vpak packaging Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway Biochem. Biophys. Res. Commun. Lenti TR30037
Lenti-vpak packaging The role ofcalgranulin Bgene on the biological behavior of squamous cervical cancer in vitro and in vivo Cancer Manag Res Lenti TR30037
Lenti-vpak packaging AGBL2 promotes cancer cell growth through IRGM-regulated autophagy and enhanced Aurora A activity in hepatocellular carcinoma Cancer Lett.2017 Lenti TR30037
Lenti-vpak packaging Interferon-γ is a master checkpoint regulator of cytokine-induced differentiation Proc. Natl. Acad. Sci. U.S.A. Lenti TR30037
Lenti-vpak packaging Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons Neuroscience Lenti TR30037P5
Lenti-vpak packaging MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism Nat Commun Lenti TR30037
Lenti-vpak packaging Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis Cancer Chemother. Pharmacol. Lenti TR30037
Lenti-vpak packaging A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability Nat. Med. Lenti TR30037
Lenti-vpak packaging β-Carotene suppresses osteoclastogenesis and bone resorption by suppressing NF-κB signaling pathway Life Sci Lenti TR30037
Lenti-vpak packaging Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer Sci Rep Lenti TR30037
Lenti-vpak packaging Targeting tissue inhibitor of metalloproteinase 1/2 using a shRNA lentiviral system offers a novel treatment strategy against hepatic fibrosis Int J Clin Exp Med Lenti TR30037
Lenti-vpak packaging TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial-mesenchymal transition Exp. Mol. Med. Lenti TR30037
Lenti-vpak packaging Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease Mol. Psychiatry Lenti TR30037
Lenti-vpak packaging TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation Oncogene Lenti TR30037
Lenti-vpak packaging MiR-122 targets VEGFC in bladder cancer to inhibit tumor growth and angiogenesis Am J Transl Res Lenti TR30037
Lenti-vpak packaging Coronin 1B serine 2 phosphorylation by p38a is critical for vascular endothelial growth factor-induced migration of human umbilical vein endothelial cells Cell. Signal. Lenti TR30037
Lenti-vpak packaging Expression of RXFP1 is Decreased in Idiopathic Pulmonary Fibrosis: Implications for Relaxin-Based Therapies Am. J. Respir. Crit. Care Med. Lenti TR30037
Lenti-vpak packaging Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinases- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis Infect. Immun. Lenti TR30037
Lenti-vpak packaging Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors Oncotarget Lenti TR30037
Lenti-vpak packaging ß-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion Am. J. Physiol. Endocrinol. Metab. Lenti TR30037
Lenti-vpak packaging Lens regeneration using endogenous stem cells with gain of visual function Nature Lenti TR30037
Lenti-vpak packaging Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts J. Biol. Chem. Lenti TR30037
Lenti-vpak packaging Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-a-lipoic acid, in human hepatocellular carcinoma cells Biochim. Biophys. Acta Dec2015 Lenti TR30037
Lenti-vpak packaging Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB Cell Metab. Lenti TR30037
Lenti-vpak packaging THE ROLE OF KDM6A/UTX IN BLADDER CANCER: FROM MUTATIONS TO THERAPEUTIC INTERVENTION thesis Lenti TR30037
Lenti-vpak packaging Insulin enhances RANKL-induced osteoclastogenesis via ERK1/2 activation and induction of NFATc1 and Atp6v0d2 Cell. Signal. Lenti TR30037
Lenti-vpak packaging SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells Autophagy Lenti TR30037
Lenti-vpak packaging Tumour-suppressive function of SIRT4 in human colorectal cancer Br. J. Cancer Lenti TR30037
Lenti-vpak packaging Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis J. Clin. Invest. Lenti TR30037
Lenti-vpak packaging ATTENUATION OF mTORC1-DRIVEN SECRETION OF LIPOPROTEINS ANDTRIACYLGLYCERIDES BY SHORT CHAIN FATTY ACIDS: MECHANISTICINSIGHT INTO THE PATHOGENESIS OF HYPERTRIGLYCERIDEMIA Thesis Lenti TR30037
Lenti-vpak packaging Phosphorylation and Inactivation of GSK3ß by Dual-Specificity Tyrosine(Y)-Phosphorylation-Regulated Kinase 1A (Dyrk1A) J. Biol. Chem. Lenti TR30037
Lenti-vpak packaging kit Carbonic-anhydrase IX expression is increased in thyroid cancer tissue and represents a potential therapeutic target to eradicate thyroid tumor-initiating cells Molecular and Cellular Endocrinology Lenti TR30037
Lenti-vpak packaging kit Phosphorylation dependent mitochondrial translocation of Nr4a3 provokes cardiomyocyte death Research Square Lenti TR30037
Lenti-vpak packaging kit FoxA2 and RNA Pol II mediate human islet amyloid polypeptide turnover in ER-stressed pancreatic β-cells The Biochemical journal Lenti TR30037
Lenti-vpak packaging kit Ectopic CD137 expression by rhabdomyosarcoma provides selection advantages but allows immunotherapeutic targeting OncoImmunology Lenti TR30037
Lenti-vpak packaging kit SP1-induced long non-coding RNA SNHG6 facilitates the carcinogenesis of chondrosarcoma through inhibiting KLF6 by recruiting EZH2 Cell death & disease Lenti TR30037
Lenti-vpak packaging kit Development of Cell-based High Throughput Luminescence Assay for Drug Discovery in Inhibiting OCT4 and DNA-PKcs Interaction Authorea  2020 Lenti TR30037
Lenti-vpak packaging kit The Transcription Factor p63 is a Direct Effector of IL-4/IL-13 Mediated Repression of Keratinocyte Differentiation J Invest Dermatol Lenti TR30037
Lenti-vpak packaging kit Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells Cell Metab. Lenti TR30037
Lenti-vpak packaging kit GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma Sci Signal Lenti TR30037
Lenti-vpak packaging kit Ovarian Cancer Cells Direct Monocyte Differentiation Through a Non-canonical Pathway Research Square Lenti TR30037
Lenti-vpak packaging kit Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma Int J Oncol Lenti TR30037
Lenti-vpak packaging kit Formononetin inhibits tumor growth by suppression of EGFR-Akt-Mcl-1 axis in non-small cell lung cancer J. Exp. Clin. Cancer Res. Lenti TR30037
Lenti-vpak packaging kit Development of a laboratory scalable process for enhancing lentivirus production by transient transfection of HEK293 adherent cultures Gene Ther. Lenti TR30037
Lenti-vpak packaging kit Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes PLoS ONE Lenti TR30037
Lenti-vpak packaging kit Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure Front. Cell Dev. Biol. Lenti TR30037
Lenti-vpak packaging kit Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization Cell Death Dis Lenti TR30037
Lenti-vpak packaging kit A rare codon-based translational program of cell proliferation Genome Biol. Lenti TR30037
Lenti-vpak packaging kit The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13 Cell. Mol. Immunol. Lenti TR30037
Lenti-vpak packaging kit Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer Aging (Albany NY) 2020 Lenti TR30037
Lenti-vpak packaging kit Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells J. Lipid Res. Lenti TR30037
Lenti-vpak packaging kit Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer Cell Death Dis Lenti TR30037
Lenti-vpak packaging kit DCLK1 INTEGRATES INDUCTION OF TRIB3, EMT, DRUG RESISTANCE, and POOR PROGNOSIS IN COLORECTAL CANCER Carcinogenesis Lenti TR30037
Lenti-vpak packaging kit Fenretinide via NOXA induction, enhanced activity of the BCL-2 inhibitor venetoclax in high BCL-2-expressing neuroblastoma preclinical models Mol. Cancer Ther. Lenti TR30037
Lenti-vpak packaging kit The chromatin remodeler SMARCD3 regulates cell cycle progression and its expression predicts survival outcome in ER+ breast cancer bioRxiv Lenti TR30037
Lenti-vpak packaging kit Endocytosis of very low-density lipoprotein particles: an unexpected mechanism for lipid acquisition by breast cancer cells bioRxiv Lenti TR30037
Lenti-vpak packaging kit TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis Nat Commun Lenti TR30037
Lenti-vpak packaging kit Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture Glia Lenti TR30037
Lenti-vpak packaging kit Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis Mol Neurodegener Lenti TR30037
Lenti-vpak packaging kit Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease Free Radic. Biol. Med. Lenti TR30037
Lenti-vpak packaging kit EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC J. Exp. Clin. Cancer Res. Lenti TR30037
Lenti-vpak packaging kit Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway Cancer Cell Int. Lenti TR30037
Lenti-vpak packaging kit Activating transcription factor 3 enhances chemosensitivity of dichloroacetic acid via p53 pathway in cervical squamous epithelial cancer cells Tropical Journal of Pharmaceutical Research Lenti TR30037
LGALS1 Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo Leukemia Lenti TL311756
LGALS3 Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states Nature Communications Lenti RC208785L4V
LGR5 Lgr5 maintains stemness and regulates cell property in nasopharyngeal carcinoma through Wnt/β-catenin signaling pathway Stem Cell Res Lenti TL311747
LIX1 LIX1 regulates YAP activity and controls gastrointestinal cancer cell plasticity J. Cell. Mol. Med. Lenti TL303518
LMBRD1 LMBD1 protein participates in cell mitosis by regulating microtubule assembly The Biochemical journal Lenti TL303512
LPA Effects of LPA1 and LPA6 on the regulation of colony formation activity in colon cancer cells treated with anticancer drugs J. Recept. Signal Transduct. Res. Lenti TL311698
LPA Involvement of LPA receptor-5 in the enhancement of cell motile activity by phorbol ester and anticancer drug treatments in melanoma A375 cells Biochem. Biophys. Res. Commun. Lenti TL311698
LPCAT3 Caspase-independent hepatocyte death: A result of the decrease of lysophosphatidylcholine acyltransferase 3 in non-alcoholic steatohepatitis J. Gastroenterol. Hepatol. Lenti RC209485L2
LPL Endocytosis of very low-density lipoprotein particles: an unexpected mechanism for lipid acquisition by breast cancer cells bioRxiv Lenti TL311692
Lrp6 Oncogenic KRAS signalling promotes the Wnt/ß-catenin pathway through LRP6 in colorectal cancer Oncogene Lenti TL706439
Ly6c1 Ly6C+ Inflammatory Monocyte Differentiation Partially Mediates Hyperhomocysteinemia-Induced Vascular Dysfunction in Type 2 Diabetic db/db Mice Arterioscler. Thromb. Vasc. Biol. Lenti TL513893
MACC1 MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer Cellular and molecular life sciences : CMLS Lenti RC224774L2
MACC1 Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells Cells Lenti RC224774L2
MAF Unraveling the transcriptional determinants of Liver Sinusoidal Endothelial Cell specialization Am. J. Physiol. Gastrointest. Liver Physiol. Lenti RC209247L2
MAGEA12 Overexpression and Implications of Melanoma-associated Antigen A12 in Pathogenesis of Human Cutaneous Squamous Cell Carcinoma Anticancer Res. Lenti TL311615V
MAGI2 Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2 Kidney International Lenti TL311600
MAMLD1 Attenuation of MAMLD1 Expression Suppresses the Growth and Migratory Properties of Gonadotroph Pituitary Adenomas Pathol. Oncol. Res. Lenti TL313623
MAN1A1 Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer Br. J. Cancer Lenti TL311595
MAP2K1 MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner J Hematol Oncol Lenti RC218460L1
MAP3K12 Intrathecal Injection of Dual Zipper Kinase shRNA Alleviating the Neuropathic Pain in a Chronic Constrictive Nerve Injury Model Int J Mol Sci Lenti TL709656
MAPRE1 EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion FASEB J. Lenti TL316980
MAPT Increased Tau Expression Correlates With IDH Mutation in Infiltrating Gliomas and Impairs Cell Migration J. Neuropathol. Exp. Neurol. Lenti RC217773L2V
MAPT miR-186 regulates chemo-sensitivity to paclitaxel via targeting MAPT in non-small cell lung cancer (NSCLC) Molecular BioSystems Lenti RC216166L1
MARK4 MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism Nat Commun Lenti TL303343
MAVS Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas Cancer Cell Lenti TL307181
MBNL1 Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization Nat Commun Lenti TL303325
MCAM CD146 interacts with galectin-3 to mediate endothelial cell migration FEBS Lett. Lenti TL311550
MCL1 MicroRNA-451 sensitizes lung cancer cells to cisplatin through regulation of Mcl-1 Mol. Cell. Biochem. Lenti RC231044L2
Mcm4 Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells Nature July 2014 Lenti TL514127
Mcm6 Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells Nature July 2014 Lenti TL510769
MDC1 BRCT-domain protein BRIT1 influences class switch recombination Proc. Natl. Acad. Sci. U.S.A. Lenti TL517490
MDM2 MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes Cancer Res. Lenti TL311529
MDM2 p16 Controls p53 Protein Expression through miR-dependent Destabilization of MDM2 Mol. Cancer Res. Lenti TL311529
MDM2 p53 participates in the protective effects of ischemic post-conditioning against OGD-reperfusion injury in primary cultured spinal cord neurons Neurosci. Lett Lenti TL311529
MECP2 MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation Cells Lenti RC202382L1
MED19 MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen bioRxiv Lenti RC206806L1
MEF2C Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells Scientific reports Lenti MR226865L4V
MEG3 Long Noncoding RNA (lncRNA) Maternally Expressed Gene 3 (MEG3) Participates in Chronic Obstructive Pulmonary Disease through Regulating Human Pulmonary Microvascular Endothelial Cell Apoptosis Med Sci Monit Lenti TL320132
MEG3 Mechanism associated with aberrant lncRNA MEG3 expression in gestational diabetes mellitus Exp Ther Med Lenti TL320132
MEG3 Skp2 regulates non-small cell lung cancer cell growth by Meg3 and miR-3163 Tumour Biol. Lenti TL320132
MEIS2 Unraveling the transcriptional determinants of Liver Sinusoidal Endothelial Cell specialization Am. J. Physiol. Gastrointest. Liver Physiol. Lenti RC222807L2
MET Role of HGF/c-Met in the treatment of colorectal cancer with liver metastasis J. Biochem. Mol. Toxicol. Lenti TL320418
Metrnl Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research Lenti RR204359L3V
METTL3 Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication J. Virol. Lenti TL303281
MEX3A The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I Cancers (Basel) 2020 Lenti TL308061
MFN2 Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts Nat Commun Lenti TL506067
MGA Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma Cancer Cell Lenti TL317004
MGRN1 E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion Oncotarget Lenti TL303267
MGRN1 Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival Mol. Cell Lenti TL702100
Micu1 miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart J Am Heart Assoc Lenti TL512307
MLH1 MicroRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homolog 1 Biosci. Rep. Lenti TL320419
MLH1 MicroRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homolog 1 Biosci. Rep. Lenti RC201607L1
MLX The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling Genes Dev. Lenti TL513600
MMP1 Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer Cancers Lenti TL311450V
MMP7 Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop Oncotarget Lenti TL311438
MMP9 MicroRNA-3713 regulates bladder cell invasion via MMP9 Sci Rep Lenti TL311436
MNAT1 MAT1 facilitates the lung metastasis of osteosarcoma through upregulation of AKT1 expression Life Sci. Lenti TL311433
MNX1 MNX1 is oncogenically upregulated in African-American prostate cancer Cancer Res. Lenti TL319509
Mpdu1 MPDU1 regulates CEACAM1 and cell adhesion in vitro and in vivo Glycoconjugate journal Lenti MR203118L3V
MPV17 The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA J. Biol. Chem. Lenti TL316619
MSLN Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells Mol. Cancer Lenti TL311377
MSLN Role of mesothelin in carbon nanotube-induced carcinogenic transformation of human bronchial epithelial cells Am. J. Physiol. Lung Cell Mol. Physiol. Lenti TL311377
MSRB3 A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability Nat. Med. Lenti TL315359
MTDH AEG-1 promotes mesenchymal transition through the activation of Rho GTPases in human glioblastoma cells Oncol. Rep. Lenti RC207238L1
MTFP1 Mitochondrial protein 18 is a positive apoptotic regulator in cardiomyocytes under oxidative stress Clin. Sci. Lenti TL307024
MUCL1 HER2 drives Mucin-like 1 to control proliferation in breast cancer cells Oncogene Lenti RC213754L1
MX2 MX2 is an interferon-induced inhibitor of HIV-1 infection Nature. 2013 Oct 24;502(7472):563-6. Lenti TL311334
MYB Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells PLoS ONE Lenti TL311329
MYC PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis OncoImmunology Lenti TL311323V
MYC A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo Cancer Cell Lenti RC201611L1V
MYC A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo Cancer Cell Lenti RC201611L3V
MYCN A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human Nat Commun Lenti MR207382L2
MYH10 Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain Mol Neurodegener Lenti TL711338
MYO1F MYO1F Regulates IgE and MRGPRX2-Dependent Mast Cell Exocytosis Journal of immunology (Baltimore, Md. : 1950) 2021 Lenti TL311296
MYO5A Actin and Myosin-dependent localization of mRNA to dendrites PLoS ONE Lenti TL311295
NANOG Low-Level Nanog Expression in the Regulation of Quiescent Endothelium Arterioscler. Thromb. Vasc. Biol. Lenti TL303039
NAV3 MiR-21 promoted proliferation and migration in hepatocellular carcinoma through negative regulation of Navigator-3 Biochem. Biophys. Res. Commun. Lenti TL311261
NDP Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT J. Clin. Invest. Lenti RC206555L2
NDP Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT J. Clin. Invest. Lenti TL316631
NEBL LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments J. Am. Soc. Nephrol. Lenti TL302993
NEFH A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes Molecular cell Lenti RC213487L3
Negative Control Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG BioRxiv Lenti PS100093V
Negative Control TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223 Bone Lenti TR30021V
Negative Control ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma Cells Lenti TR30021V
Negative Control Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure Front. Cell Dev. Biol. Lenti TR30021
Negative Control Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity Blood Adv Lenti PS100093V
Negative Control Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1 PLoS Genet. Lenti TR30021V
Negative Control Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts Br. J. Dermatol. Lenti PS100093V
Negative Control Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer Cell Lenti TR30021
Negative Control Down-regulation of 14-3-3 zeta sensitizes human glioblastoma cells to apoptosis induction Apoptosis Lenti TR30021V
NEK7 EK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury Front Mol Neurosci Lenti TL515241
NELFE Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma Cancer Cell Lenti RC208658L2
NEUROD1 Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice Nat. Neurosci Lenti TL311201
NEUROD1 Rapid neurogenesis through transcriptional activation in human stem cells Mol. Syst. Biol. Lenti TL311201
NF1 Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness Oncogene Lenti TL509076
NFATC2 NFATC2 Modulates Radiation Sensitivity in Dermal Fibroblasts From Patients With Severe Side Effects of Radiotherapy Frontiers in oncology Lenti TL311198
NFE2L2 c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation Theranostics Lenti TL311194
NFE2L2 NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping inMus musculus Elife Lenti MR226717L1
NFE2L2 Nrf2 deficiency exacerbates ochratoxin A-induced toxicity in vitro and in vivo Toxicology Lenti TL311194
Nfe2l2 Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance Cancer Discov Lenti TL515053
NGB Prodromal Alzheimer\'s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer\'s Pathology Frontiers in neuroscience Lenti TL503454
NGFR Polarized cells display asymmetric release of extracellular vesicles Traffic (Copenhagen, Denmark) 2020 Lenti RC207966L2
NGFR Effects of p75 neurotrophin receptor on regulating hypoxia-induced angiogenic factors in retinal pigment epithelial cells Mol. Cell. Biochem. Lenti TL311178
NGFR Monitoring signaling by the p75(NTR) receptor utilizing a caspase-3 activation assay amenable to small-molecule screening. Assay and drug development technologies Lenti RC207966L1V
NLGN2 Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine Transl Psychiatry Lenti TL302944V
NMU The YAP1-NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target Cancers (Basel) 2019 Lenti TL311154
NNAT Neuronatin is a modifier of estrogen receptor-positive breast cancer incidence and outcome Breast Cancer Res. Treat. Lenti RC200328L3
NOG Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology Proc. Natl. Acad. Sci. U.S.A. Lenti MR225276L2V
NOP2 A novel AHI-1-BCR-ABL-DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy Leukemia Lenti TL311150
NOS2 TNF-α/IL-1β-licensed mesenchymal stromal cells promote corneal allograft survival via myeloid cell-mediated induction of Foxp3+ regulatory T cells in the lung FASEB J. Lenti TL709254
NOS2 Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells Nitric Oxide Lenti RC211819L1
NOTCH1 Notch pathway regulates osimertinib drug‐tolerant persistence in EGFR ‐mutated non–small‐cell lung cancer Cancer Science Lenti TL302916V
NOVA2 Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening Cell Lenti RC216200L1V
NOVA2 Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening Cell Lenti RC216200L2V
NOVA2 Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening Cell Lenti RC216200L1
NOVA2 Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening Cell Lenti RC216200L2
NOVA2 Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening Cell Lenti TL508674
NOX4 Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction Cancers Lenti TL302911
NOX4 Nox4 regulates InsP 3 receptor‐dependent Ca 2+ release into mitochondria to promote cell survival EMBO J Lenti TL302911V
NOXO1 NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD Nat Metab Lenti MR205276L1
NPC1 NPC1 enables cholesterol mobilization during long-term potentiation that can be restored in Niemann-Pick disease type C by CYP46A1 activation EMBO Rep. Lenti TL311127
NPLOC4 A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways Lenti RC205829L1V
NR1H3 HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD Sci Rep Lenti TL320630
NR2F2 Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis Nat Commun Lenti RC206753L2
NR3C1 ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the , MIF Immune Susceptibility Locus Arthritis & rheumatology (Hoboken, N.J.) 2021 Lenti TL320374
nr3c1 Glucocorticoid receptor beta increases migration of human bladder cancer cells Oncotarget Lenti TL320374
NR4A1 RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells FASEB J. Lenti TL320381
Nr4a1 ß-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion Am. J. Physiol. Endocrinol. Metab. Lenti TL711049
Nr4a1 Bile Acids Regulate Nuclear Receptor (Nur77) Expression and Intracellular Location to Control Proliferation and Apoptosis Mol. Cancer Res. Lenti TL711049
NR4A2 NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk J. Neurosci. Lenti MR226280L1
NR4A2 NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk J. Neurosci. Lenti TL501521
NRP1 Combination of NRP1-mediated iRGD with 5-fluorouracil suppresses proliferation, migration and invasion of gastric cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Lenti TL311093V
Nrxn3 Neurexin 3α in the Central Amygdala has a Role in Orofacial Varicella Zoster Pain. Neuroscience Lenti TL712174V
NSMF RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters Virology Lenti TL317072
NTRK2 Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells Oncogenesis Lenti TL320436V
NUMA1 Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation Nat. Struct. Mol. Biol. Lenti TL311065
OCIAD2 OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma Carcinogenesis Lenti TL311040
OCLN Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice Biochim. Biophys. Acta Lenti TL311039
OGA O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth Oncogene Lenti TL315637
OGT O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness OncoTargets and therapy Lenti TL302811
OGT The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis Nat Commun Lenti RC224481L1
Ogt Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells Cell. Signal. Lenti MR211521L1
OMA1 Stress-triggered Activation of the Metalloprotease Oma1 Involves Its C-terminal Region and Is Important for Mitochondrial Stress Protection in Yeast The Journal of Biological Chemistry Lenti TL302802V
One-Wash Lentivirus Titer Kit LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis EMBO reports Lenti TR30038
One-Wash Lentivirus Titer Kit Glutamate receptor ionotropic, kainate 1 serves as a novel tumor suppressor of colorectal carcinoma and predicts clinical prognosis Exp Ther Med Lenti TR30038
ONECUT2 ONECUT2 is a driver of neuroendocrine prostate cancer Nat Commun Lenti RC211951L3
ONECUT2 ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis SSRN Lenti RC211951L1
OPN1LW Opsin 3-Gαs Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2 Am J Respir Cell Mol Biol Lenti RC224868L4V
ORAI3 Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation Nature communications Lenti RC202325L1
ORAI3 Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation Nature communications Lenti TL307587
P2RX1 Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse Blood Lenti RC207924L3V
P2RY14 UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells Placenta Lenti TL310644V
P2RY2 P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling Circ. Res. Lenti RC223931L2
P2RY2 P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling Circ. Res. Lenti TL302717
PA2G4 ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells Journal of Biological Chemistry Lenti TL310638
PADI4 Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix Nat Commun Lenti TL310630
Pafah1b1 NuMA1 promotes axon initial segment assembly through inhibition of endocytosis The Journal of Cell Biology Lenti MR206439L3V
PAK1 Pak1 pathway hyper-activation mediates resistance to endocrine therapy and CDK4/6 inhibitors in ER+ breast cancer NPJ Breast Cancer Lenti RC225947L4V
PARP1 Transcriptional Regulation of CCL2 by PARP1 Is a Driver for Invasiveness in Breast Cancer Cancers (Basel) 2020 Lenti TL315488V
PARP1 Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1 J. Virol. Lenti TL709663
PBK PDZ-Binding Kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma Transl Oncol Lenti RC203295L2V
PBRM1 Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling Cell Rep Lenti TL517996
pCas-Guide Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes Nature Lenti GE100003
PCDH15 Origins and Proliferative States of Human Oligodendrocyte Precursor Cells Cell Lenti TL302649V
PCDH17 Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma Tumour Biol. Lenti TL310584V
PCDH17 Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma Tumour Biol. Lenti RC206968L1
PCLAF PCNA-associated factor P15PAF , targeted by FOXM1, predicts poor prognosis in high-grade serous ovarian cancer patients Int. J. Cancer Lenti RC216104L3
PD-L1 Leukemic Extracellular Vesicles Induce Chimeric Antigen Receptor T Cell Dysfunction in Chronic Lymphocytic Leukemia Molecular Therapy Lenti RC213071L4
PD-L1 Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells Cancer Immunol. Immunother. Lenti RC213071L2V
PD1 m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade Nat Commun Lenti RC210364L2
PDCD1 Engineering PD-1-Presenting Platelets for Cancer Immunotherapy Nano Lett. Lenti MR227347L4
Pdcd1 Blockade of Tumor-Expressed PD-1 Promotes Lung Cancer Growth OncoImmunology Lenti MR227347L2V
PDCD10 Endothelial cell clonal expansion in the development of cerebral cavernous malformations Nat Commun Lenti RC205095L2
PDCD10 Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma J. Neurooncol. Lenti TL302576
PDCD10 miRNA-24-3p promotes cell proliferation and regulates chemosensitivity in head and neck squamous cell carcinoma by targeting CHD5 Future Oncol Lenti RC221815L1
PDCD10 MicroRNA-425-5p regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10 J. Cell. Mol. Med. Lenti RC221815L1
PDE4B Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition Biochim. Biophys. Acta Lenti RC218324L3
PDE5A Sildenafil prevents HDACi-induced Epstein-Barr virus reactivation through the PKG pathway in NK/T cell lymphoma; potential implications for HDACi-mediated fatal complications Antiviral research Lenti TL316826
PDE5A Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy Clin. Cancer Res. Lenti TL316826
PDGFB Stromal platelet-derived growth factor receptor-β signaling promotes breast cancer metastasis in the brain Cancer Research Lenti TL501604
Pdhb Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue Cell metabolism Lenti MR205484L3V
Pdhb Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue Cell metabolism Lenti MR205484L4V
PDX1 Development of new preclinical models to advance adrenocortical carcinoma research Endocr. Relat. Cancer Lenti RC222354L2
PECAM1 PECAM1 Combines With CXCR4 to Trigger Inflammatory Cell Infiltration and Pulpitis Progression Through Activating the NF-κB Signaling Pathway Frontiers in Cell and Developmental Biology Lenti TL711400V
PECAM1 CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin Cell Host & Microbe Lenti RC208654L3
PECAM1 CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin Cell Host & Microbe Lenti MR227044L4
PECAM1 Cell-specific targeting by Clostridium perfringens β-toxin unraveled: the role of CD31 as the toxin receptor bioRxiv Lenti RC208654L3
PEG10 PEG10 counteracts signaling pathways of TGF-β and BMP to regulate growth, motility and invasion of SW1353 chondrosarcoma cells J. Bone Miner. Metab. Lenti RC229935L1
PER1 Light affects behavioral despair involving the clock gene Period 1 bioRxiv Lenti TL501619
Peroxiredoxin 5 Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis Cells Lenti RC210709L3
PGK1 Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis Cell Rep Lenti RC211172L1
PGR A mouse model engineered to conditionally express the progesterone receptor-B isoform Genesis Lenti MR227418L1
PGRMC1 PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca2+ Entry Via STIM2 in MDA-MB-231 Cells Int J Mol Sci Lenti TL316942
PHGDH Serine Biosynthesis Pathway Supports MYC-miR-494-EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells Cancers (Basel) 2020 Lenti TL507159
PI3 Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2 Cellular and Molecular Gastroenterology and Hepatology Lenti RC203136L1V
PI3 Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice Sci Rep Lenti RC203136L1V
PI4KA A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis Cell Rep Lenti TL510615
PIK3CA Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer Clin. Cancer Res. Lenti RC213112L1
PIM2 PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity J. Clin. Invest. Lenti MR222342L2
PIP5K1A Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma Int J Oncol Lenti RC227689L2V
PKM PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma J. Exp. Clin. Cancer Res. Lenti TL302462
PLAAT4 RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer Am J Cancer Res Lenti TL320510
PLCB4 Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs Nat Commun Lenti TL310374
PLCG2 The Alzheimer\'s disease-associated protective Plcγ2-P522R variant promotes immune functions Molecular neurodegeneration Lenti RC200442L1
PLCG2 The Alzheimer′ s disease-associated protective Plcγ2-P522R variant promotes beneficial microglial functions bioRxiv Lenti RC200442L1
pLenti-C-mGFP Guanylate Binding Protein 5 (GBP5) regulates synovial fibroblast mediated inflammation and tissue destruction in rheumatoid arthritis Arthritis & Rheumatology Lenti PS100071V
pLenti-C-mGFP Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma Int J Oncol Lenti PS100071V
pLenti-C-mGFP Increased Tau Expression Correlates With IDH Mutation in Infiltrating Gliomas and Impairs Cell Migration J. Neuropathol. Exp. Neurol. Lenti PS100071V
pLenti-C-mGFP-P2A-Pur RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway OncoTargets and therapy Lenti PS100093V
pLenti-C-mGFP-P2A-Puro 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma Cell Rep Lenti PS100093V
pLenti-C-mGFP-P2A-Puro GRK5 is an Essential Co-repressor for Cardiac Mineralocorticoid Receptor Antagonism induced by Finerenone but not Eplerenone preprints Lenti PS100093V
pLenti-C-Myc-DDK Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice Sci Rep Lenti PS100064V
pLenti-C-Myc-DDK Inhibition of endoglin exerts anti-tumor effects through the regulation of non-Smad TGF-β signaling in angiosarcoma J. Invest. Dermatol. Lenti PS100064V
pLenti-C-Myc-DDK-P2A- Puro DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the β-catenin pathway Research Square Lenti PS100092V
PLK4 Polo‑like kinase 4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma Oncol. Rep. Lenti TL320644V
PNPLA2 Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling Biochim Biophys Acta Mol Cell Biol Lipids Lenti TL302393
PNPLA2 Grasp55-/- mice display impaired fat absorption and resistance to high-fat diet-induced obesity Nat Commun Lenti RC205708L3
PNPLA2 Alternative splicing switches STIM1 targeting to specialized membrane contact sites and modifies SOCE bioRxiv Lenti RC205708L3
Positive Control Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis Nat Commun Lenti PS100071V5
POU3F1 Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration Nat Commun Lenti TL712899
POU3F2 Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia Mol. Psychiatry Lenti TL310273V
POU5F1 OCT4 accelerates tumorigenesis through activating JAK/STAT signaling in ovarian cancer side population cells Cancer Manag Res Lenti RC211998L1
POU5F1 OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells Oncogene Lenti TL310267
PPARD Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion bioRxiv Lenti RC214735L3
PPARD Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion bioRxiv Lenti MR207001L3
PPARG Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow Neoplasia (New York, N.Y.) 2021 Lenti TL320459V
Pparg Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG BioRxiv Lenti MR208132L4V
PPARGC1A AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species Cell Rep Lenti MR210710L2
PPARGC1A Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR-YY1-PGC1a pathway Free Radic. Biol. Med. Lenti TL509292
PPM1G Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase Oncogene Lenti RC213685L1
PPP2CA AIM2 in regulatory T cells restrains autoimmune diseases Nature Lenti MR204384L4
PPP2CA PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+human leukemia Sci Transl Med Lenti TL310229
PRDM1 NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells Front. Immunol. Lenti RC217363L1V
PRDM1 Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1 Mol. Immunol. Lenti TL510199
PRDX4 A reference map of the human proinsulin biosynthetic interaction network bioRxiv Lenti TL510004
PRKAB1 AMP kinase promotes glioblastoma bioenergetics and tumour growth Nat. Cell Biol. Lenti TL501734
PRKDC PRKDC regulates chemosensitivity and is a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients Oncol. Rep. Lenti TL320478
PRLR Prolactin promotes fibrosis and pancreatic cancer progression Cancer Res. Lenti TL310169
PRMT2 Huntingtin-mediated axonal transport requires arginine methylation by PRMT6 Cell reports Lenti TL500997
PRMT7 PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation Mol. Biol. Cell Lenti RC201672L2
PRMT7 PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation Mol. Biol. Cell Lenti RC201672L1
PRNP Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis J. Pineal Res. Lenti TL302273
PRNP Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells Cell Death Dis Lenti TL302273
PROM1 CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche Cancer Growth Metastasis Lenti TL501745
PRSS21 Proteolytic activation of the protease-activated receptor (PAR)-2 by the GPI-anchored serine protease testisin J. Biol. Chem. Lenti TL310139
PSMB5 A conserved SUMO-Ubiquitin pathway directed by RNF4/SLX5-SLX8 and PIAS4/SIZ1 drives proteasomal degradation of topoisomerase DNA-protein crosslinks bioRxiv Lenti RC209326L3
PSMB5 Inhibition of store-operated calcium entry by sub-lethal levels of proteasome inhibition is associated with STIM1/STIM2 degradation Cell Calcium Lenti TL310110
PSMC5 Hypoxia-induced increase in Sug1 leads to poor post-transplantation survival of allogeneic mesenchymal stem cells FASEB J. Lenti TL711271V
PTEN PTEN is a Predictive Biomarker of Trastuzumab Resistance and Prognostic Factor in HER2-overexpressing Gastroesophageal Adenocarcinoma Research Square Lenti TL320498
PTEN Clinical and functional characterization of CXCR1/CXCR2 biology in the relapse and radiotherapy resistance of primary PTEN-deficient prostate carcinoma NAR Cancer Lenti TL320498
PTEN PPARgamma agonists sensitize PTEN-deficient resistant lung cancer cells to EGFR tyrosine kinase inhibitors by inducing autophagy Eur. J. Pharmacol. Lenti TL320498
PTGES Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells Nitric Oxide Lenti RC202405L1
PTGES mPGES-1 in prostate cancer controls stemness and amplifies EGFR-driven oncogenicity Endocr. Relat. Cancer Lenti RC202405L1
PTGS2 Construction of COX-2 short hairpin RNA expression vector and its inhibitory effect on hepatic fibrosis Biotechnology & Biotechnological Equipment Lenti TL710033
PTP4A3 Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor Oncotarget Lenti TL320652
PTPN1 Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes Sci Transl Med Lenti TL310067V
PTPN1 HER2 Phosphorylates and Destabilizes Pro-Apoptotic PUMA, Leading to Antagonized Apoptosis in Cancer Cells PLoS ONE Lenti RC204902L1V
PUF60 PUF60 accelerates the progression of breast cancer through downregulation of PTEN expression Cancer Manag Res Lenti TL307443
PURA Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity Acta Neuropathol. Lenti TL310036V
RAB11A Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity J. Virol. Lenti TL310015
RAB11A HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system J. Virol. Lenti TL310015
RAB5A Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity J. Virol. Lenti TL309987
RAB5A HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system J. Virol. Lenti TL309987
RAB7A Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity J. Virol. Lenti TL309983
RAB7A HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system J. Virol. Lenti TL309983
RAB7A Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells Oncotarget Lenti RC201776L1
RAC1 CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility Elife Lenti TL320503
RACK1 AIM2 in regulatory T cells restrains autoimmune diseases Nature Lenti MR204575L3
RAD18 AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress Oncogene Lenti TL302132
RAD18 High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression Biomed. Pharmacother. Lenti TL302132
RAD18 High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression Biomed. Pharmacother. Lenti RC201700L1
RAD21 ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis Sci Adv Lenti TL501846
RALA The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer Breast cancer research : BCR Lenti TL309957V
RALA The Small G-Protein RalA Promotes Progression and Metastasis of Triple Negative Breast Cancer Research Square Lenti TL309957V
RALB The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer Breast cancer research : BCR Lenti TL309956V
RALB The Small G-Protein RalA Promotes Progression and Metastasis of Triple Negative Breast Cancer Research Square Lenti TL309956V
RANBP2 Ankyrin-G induces nucleoporin RanBP2/Nup358 to associate with the axon initial segment of neurons J. Cell. Sci. Lenti TL501860
RANGAP1 The C9orf72 repeat expansion disrupts nucleocytoplasmic transport Nature Lenti RC204223L2
RAPGEF2 Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2 Kidney International Lenti TL316875
RAPGEF4 Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells Curr. Biol. Lenti TL509420
RARA Retinoid receptor turnover mediated by sumoylation, ubiquitination and the valosin-containing protein is disrupted in glioblastoma Sci Rep Lenti RC200430L1
RASA2 Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers Cancer Cell Lenti RC224076L3
RASIP1 Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions Development Lenti TL302100
RBL1 Association between copy-number alteration of +20q, -14q and -18p and cross-sensitivity to tyrosine kinase inhibitors in clear-cell renal cell carcinoma Cancer Cell Int Lenti RC207017L3
RBL1 Intra-cisterna magna delivery of an AAV vector with the GLUT1 promoter in a pig recapitulates the physiological expression of SLC2A1 Gene Ther Lenti RC207017L3V
RBM3 Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain Dev. Neurosci. Lenti TL309915
RBM38 RBM38 induces SIRT1 expression during hypoxia in non-small cell lung cancer cells by suppressing MIR34A expression Biotechnol. Lett. Lenti TL317301V
RBM5 Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons Neuroscience Lenti TL704115
RBPJ Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway JCI Insight Lenti TL512813V
RBPJ Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a Nat Commun Lenti TL512813
RETNLA Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension Hypertension Lenti TL711770
RFX7 The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity Nat. Immunol. Lenti RC211086L1
RIOK1 Targeting posttranslational modifications of RioK1 inhibits the progression of colorectal and gastric cancers bioRxiv Lenti TL320739
RIPK3 A novel neurodegenerative spectrum disorder in patients with MLKL deficiency Cell Death Dis Lenti RC209549L3
RNF144A RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2 Cell Death Differ. Lenti TL309788
RNF144A RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells Oncotarget Lenti TL309788
RORA Sertoli cell specific knockdown of RAR-related orphan receptor (ROR) alpha at puberty reduces sperm count in rats Gene Lenti TL705407
RPA3 Elevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival Dig. Dis. Sci. Lenti TL316699
RPS27A RPS27a enhances EBV-encoded LMP1-mediated proliferation and invasion by stabilizing of LMP1 Biochem. Biophys. Res. Commun. Lenti TL309716
RRM2 RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer Cancer cell international Lenti TL309700
RSF1 RSF1 regulates the proliferation and paclitaxel resistance via modulating NF-κB signaling pathway in nasopharyngeal carcinoma J Cancer Lenti RC218432L2
RTEL1 RTEL1 Influences the Abundance and Localization of TERRA RNA bioRxiv Lenti RC214507L3
Rtn4 A universal approach to investigate circRNA protein coding function Scientific Reports Lenti MR209681L3V
RUNX1 rs11671784 G/A variation in miR-27a decreases chemo-sensitivity of bladder cancer by decreasing miR-27a and increasing the target RUNX-1 expression Biochem. Biophys. Res. Commun. Lenti RC223809L1
RUNX3 Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation J. Clin. Invest. Lenti TL309682
RXFP1 Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1 Theranostics Lenti TL301865
RXFP1 Expression of RXFP1 is Decreased in Idiopathic Pulmonary Fibrosis: Implications for Relaxin-Based Therapies Am. J. Respir. Crit. Care Med. Lenti RC211338L1
RXRB Prominent role of RAB39A-RXRB axis in cancer development and stemness Oncotarget Lenti RC200516L3
S100A14 Increased S100A15 expression and decreased DNA methylation of its gene promoter are involved in high metastasis potential and poor outcome of lung adenocarcinoma Oncotarget Lenti TL318900
S100A8 Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis International Journal of Molecular Sciences Lenti TL519129
S100A9 S100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism Cancer Manag Res Lenti TL316713
S100A9 The role ofcalgranulin Bgene on the biological behavior of squamous cervical cancer in vitro and in vivo Cancer Manag Res Lenti TL316713
S100G 17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation Biosci. Rep. Lenti TL709169
S100G Modulation effects of black-vinegar based supplement against a high-fat dietary habit: antiobesity/hypolipidemic, antioxidative, and energy-metabolism effects J. Sci. Food Agric. Lenti TL709169
SAA3 Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts J. Biol. Chem. Lenti TL501964
SALL1 SALL1 expression in acute myeloid leukemia Oncotarget Lenti TL309658
SALL4 Inflammatory Micro-environment Contributes to Stemness Properties and Metastatic Potential of HCC via the NF-κB/miR-497/SALL4 Axis Mol Ther Oncolytics Lenti TL301854
SALL4 Inflammatory microenvironment contributes to stemness properties and metastatic potential of hepatocellular carcinoma via NF-κB/miR-497/SALL4 axis Molecular Therapy - Oncolytics Lenti TL301854
SAV1 Dysregulation of PI3K and hippo signaling pathways synergistically induces chronic pancreatitis via Ctgf upregulation The Journal of clinical investigation Lenti MR206033L4
SCG3 Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells Mol. Endocrinol Lenti TL516044
Scrambled Control Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer Cancers Lenti TR30021
Scrambled Control MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism Cancer cell Lenti TR30021
Scrambled Control Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) Scientific reports Lenti TR30021
Scrambled Control Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer Nature communications Lenti TR30033
Scrambled Control Prodromal Alzheimer\'s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer\'s Pathology Frontiers in neuroscience Lenti TR30021
Scrambled Control Alzheimer\'s-associated PU.1 expression levels regulate microglial inflammatory response Neurobiology of disease Lenti TR30013
Scrambled Control Analysis of ADAM9 Regulation and Function in Vestibular Schwannoma Primary Cells Research Square Lenti TR30021V
Scrambled Control UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells Placenta Lenti TR30021V
Scrambled Control GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma Sci Signal Lenti TR30021
Scrambled Control Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT J. Clin. Invest. Lenti TR30021
Scrambled Control Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α Mol. Cancer Res. Lenti TR30021
Scrambled Control GRSF1 suppresses cell senescence Aging (Albany NY) 2018 Lenti TR30021V
SDC1 Sphingosine 1-phosphate regulates proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells via syndecan-1 Prog. Biophys. Mol. Biol.2017 Lenti TL309598
SDC1 Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop Oncotarget Lenti TL309598
SDCBP Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase Oncogenesis Lenti TL309594
SDCBP Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness Am. J. Respir. Cell Mol. Biol. Lenti RC215390L1
SDCBP Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells Oncotarget Lenti TL309594
SDCBP Syntenin regulates TGF-ß1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-ß type I receptor internalization Oncogene Lenti TL309594
SDCBP2 Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness Am. J. Respir. Cell Mol. Biol. Lenti RC218898L2
Sec22b Identification of host factors involved in coronavirus replication by quantitative proteomics analysis Proteomics Lenti RR213696L3V
SEMA3C Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development Sci Rep Lenti RC205269L1
SEMA6A Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A Proc. Natl. Acad. Sci. U.S.A. Lenti TL510568
SENP2 SUMOylation determines the voltage required to activate cardiac IKs channels Proc. Natl. Acad. Sci. U.S.A. Lenti TL517117
SENP2 Accumulation of histone variant H3. 3 with age is associated with profound changes in the histone methylation landscape Nucleic Acids Research Lenti TL517117
SERPINH1 Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer Cancer Biol Med Lenti TL316478
SH2D3C Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation Neuroscience Lenti TL502696
SH3BP2 Myo1f, an Unconventional Long-Tailed Myosin, Is a New Partner for the Adaptor 3BP2 Involved in Mast Cell Migration Front Immunol Lenti RC205759L2
SIRT6 Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma Biochem. Biophys. Res. Commun Lenti RC202833L1
SKA2 Upregulation of microRNA‑520a‑3p inhibits the proliferation, migration and invasion via spindle and kinetochore associated 2 in gastric cancer Oncology Letters Lenti RC222296L3
SKP2 OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells Oncogene Lenti TL301684
SLC10A1 Apical Sodium-Dependent Bile Acid Cotransporter, A Novel Transporter of Indocyanine Green, and Its Application in Drug Screening Int J Mol Sci Lenti RC210241L2
SLC10A1 Role of Sodium Taurocholate Cotransporting Polypeptide as a New Reporter and Drug-Screening Platform: Implications for Preventing Hepatitis B Virus Infections Mol Imaging Biol Lenti RC210241L2
SLC10A1 N-linked glycosylation is not essential for sodium taurocholate cotransporting polypeptide to mediate hepatitis B virus infection in vitro J. Virol. Lenti TL309420
SLC10A2 Apical Sodium-Dependent Bile Acid Cotransporter, A Novel Transporter of Indocyanine Green, and Its Application in Drug Screening Int J Mol Sci Lenti RC221202L2
SLC15A2 Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells Nat Commun Lenti TL503323
SLC16A1 Metabolic heterogeneity confers differences in melanoma metastatic potential Nature Lenti TL309405
SLC17A5 Nitrate uptake and metabolism in human skeletal muscle cell cultures Nitric Oxide Lenti TL309394
SLC1A5 Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation Cancer Cell Lenti TL516694
Slc2a1 The insulin-like growth factor I receptor regulates glucose transport by astrocytes Glia Lenti TL511086
SLC2A1 A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect Nat Commun 3608 5 . April 2014 Lenti TL309344
SLC5A1 Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors Pharmaceuticals (Basel, Switzerland) 2021 Lenti RC221312L1V
Slc5a1 Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity Lenti MR209884L3V
SLC5A2 Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors Pharmaceuticals (Basel, Switzerland) 2021 Lenti RC224822L1V
SLC5A2 Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models. The Journal of pharmacology and experimental therapeutics Lenti RC224822L1V
SLC5A2 Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level. The Journal of pharmacology and experimental therapeutics Lenti RC224822L1V
SLC7A11 System χc- overexpression prevents 2-deoxy-d-ribose-induced β-cell damage Free Radic. Biol. Med. Lenti RR208495L4
SLIT1 Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway BMC Cancer Lenti TL502069
SLITRK2 Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior Cell Rep Lenti TL514163
SLITRK5 Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior Cell Rep Lenti TL505056
SMAD2 Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification Cell Death Differ. Lenti RR212493L2
SMAD3 Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance Oncogene Lenti TL309254
SMC1A ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis Sci Adv Lenti TL513033
SMO Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway J. Cell. Biochem. Lenti TL309234
SMO Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models Med. Sci. Monit Lenti MR210692L2
SMO Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models Med. Sci. Monit Lenti TL510788
SMOX Increased polyamines as protective disease modifiers in Congenital Muscular Dystrophy Hum. Mol. Genet. Lenti RC214652L2
SMPD3 The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells Br. J. Haematol Lenti TL301492
SNAI1 Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance Oncogene Lenti TL309226
SNAI1 FBXO22 possesses both pro-tumorigenic and anti-metastatic roles in breast cancer progression Cancer Res. Lenti TL309226
SNAI1 Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer Cancer Res. Lenti MR203505L2V
SNAI1 Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression PLoS Genet. Lenti TL502087
SNAI2 SLUG Directs the Precursor State of Human Brain Tumor Stem Cells Cancers (Basel) 2019 Lenti RC202365L1
SNAP25 A role for alternative splicing in circadian control of exocytosis and glucose homeostasis Genes & Development Lenti RC212596L3V
SNCA a-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation Proc. Natl. Acad. Sci. U.S.A. Lenti TL710189
SNX27 STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness Clinical and Translational Medicine Lenti RC218477L4V
SOD2 NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation. International journal of molecular sciences Lenti TL309190V
SORL1 SORLA regulates endosomal trafficking and oncogenic fitness of HER2 Nat Commun Lenti TL309181
SORL1 SORLA-driven endosomal trafficking regulates the oncogenic fitness of HER2 bioRxiv Lenti TL309181
SOX10 m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade Nat Commun Lenti RC203545L2
SOX2 Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma International Journal of Oncology Lenti RC200757L3
SOX2 Arsenic promotes the COX2/PGE2-SOX2 axis to increase the malignant stemness properties of urothelial cells Int. J. Cancer Lenti TL309173
Sox2 YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells Cancer Res.2017 Lenti TL515613
SOX7 Sox7 is involved in antibody-dependent endothelial cell activation and renal allograft injury via the Jagged1-Notch1 pathway Exp. Cell Res. Lenti TL301454
SOX9 Sox9 regulates the luminal stem/progenitor cell properties of salivary glands Experimental Cell Research Lenti TL511411
SOX9 Incomplete radiofrequency ablation promotes the development of CD133+ cancer stem cells in hepatocellular carcinoma cell line HepG2 via inducing SOX9 expression HBPD INT Lenti TL309170
SOX9 SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas J. Invest. Dermatol. Lenti TL309170
SP1 Resveratrol Represses Pokemon Expression in Human Glioma Cells Molecular Neurobiology Lenti TL301453
SP7 Synergistic Effects of Controlled-Released BMP-2 and VEGF from nHAC/PLGAs Scaffold on Osteogenesis BioMed Research International Lenti TL514041
SPANXD The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma Scientific reports Lenti TL318845
SPAST Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells Neuroscience Lenti TL511715
SPI1 Transcriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13 Genesis Lenti TL316738
Spry4 Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells Development & Reproduciton Lenti TL509780
SQLE Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target Sci Transl Med Lenti TL309122
SQSTM1 Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene Cell Death Dis Lenti TL515047
SREBF2 miR-33a Mediates the Anti-Tumor Effect of Lovastatin in Osteosarcoma by Targeting CYR61 Cell. Physiol. Biochem. Lenti TL309116
SRF Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation Cell Metab. Lenti MR208120L2
SRSF5 The evolution of alternative splicing in glioblastoma under therapy Genome biology Lenti RC218652L2
Srsf7 Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells. The journal of medical investigation : JMI Lenti RR204422L3V
ST8SIA3 Glycolipids Recognized by A2B5 Antibody Promote Proliferation, Migration, and Clonogenicity in Glioblastoma Cells Cancers (Basel) 2019 Lenti TL301359
STAT1 Resistance to histone deacetylase inhibitors confers hypersensitivity to oncolytic reovirus therapy Blood Adv Lenti TL301349V
STAT1 Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells Nat Commun Lenti TL301349
STAT3 PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis OncoImmunology Lenti TL301348V
STAT3 Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway Biochem. Biophys. Res. Commun. Lenti TL301348
STAT3 Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A Blood Lenti TL301348
STC1 Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance Cancer cell Lenti MR203105L1
STIM1 STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons Cells Lenti TL309049
STIM2 STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons Cells Lenti TL301342
STING1 Epigenetic reprogramming of tumor cell-intrinsic STING function sculpts antigenicity and T cell recognition of melanoma Proceedings of the National Academy of Sciences of the United States of America Lenti TL307876V
STIP1 Stress-induced phosphoprotein 1 promotes pancreatic cancer progression through activation of the FAK/AKT/MMP signaling axis Pathology - Research and Practice Lenti TL309048
STK19 Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis Cell Lenti RC219373L3
STMN1 The microRNA-210-Stathmin1 Axis Decreases Cell Stiffness to Facilitate the Invasiveness of Colorectal Cancer Stem Cells Cancers Lenti RC205073L3
Stub1 STUB1 directs FOXQ1-mediated transactivation of Ldha gene and facilitates lactate production in mouse Sertoli cells. Cell and tissue research Lenti RR213174L3V
STX12 Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs Nat Commun Lenti TL301328
Stxbp5 Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn J. Neurosci. Lenti TL518079
STXBP6 STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness Clinical and Translational Medicine Lenti RC209598L3V
SUCNR1 Pulmonary Neuroendocrine Cells Sense Succinate to Stimulate Myoepithelial Cell Contraction Developmental cell Lenti RC205888L1V
SULT1A1 Identification and targeting of selective vulnerability rendered by tamoxifen resistance Breast Cancer Res. Lenti RC201601L1
SYK Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities Front Cell Neurosci Lenti TL320543
SYK SYK-targeted dendritic cell-mediated cytotoxic T lymphocytes enhance the effect of immunotherapy on retinoblastoma J. Cancer Res. Clin. Oncol. Lenti RC200413L3
Syvn1 The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology J. Biol. Chem. Lenti TL704173
TARDBP Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients Acta Neuropathol. Lenti RC210639L2
TBL1X Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma haematol Lenti TL316751
TBX20 Tbx20 controls the expression of the KCNH2 gene and of hERG channels Proc. Natl. Acad. Sci. U.S.A Lenti RC212412L2
TBX20 Tbx20 controls the expression of the KCNH2 gene and of hERG channels Proc. Natl. Acad. Sci. U.S.A Lenti TL503288
TBX21 Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria Cell Rep Lenti RC207902L4V
TBX5 Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells Scientific reports Lenti MR227369L4V
TBX5 Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis Nature Communications Lenti RC216520L2V
TBX5 Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis Nat Commun Lenti RC216520L2
Tcf7l2 Macrophage TCF-4 Coactivates p65 to Potentiate Chronic Inflammation and Insulin Resistance in Mice Clin. Sci. Lenti MR207325L1
TCOF1 Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance Radiat. Res. Lenti TL704731V
TDP2 TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency Mol. Cell Lenti RC202015L1
TDP2 Topoisomerase 2 [beta]-dependent nuclear DNA damage shapes extracellular growth factor responses through AKT phosphorylation dynamics to control virus latency bioRxiv Lenti RC202015L1
TEAD1 YAP1 plays a key role of the conversion of normal fibroblasts into cancer-associated fibroblasts that contribute to prostate cancer progression J. Exp. Clin. Cancer Res. Lenti TL513813
TEAD1 Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma Nat Commun Lenti RC215492L1
TERF2 Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury Communications biology Lenti RC223601L1
TET1 Vitamin C Promotes Astrocyte Differentiation Through DNA Hydroxymethylation Stem Cells Lenti TL706196
TET2 Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation Sci Adv Lenti TL513547
TET2 Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice Oncotarget Lenti RC215770L1
TET2 Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice Oncotarget Lenti TL303734
TFAM HO-1/CO system and embryonic stem cell differentiation and maturation into cardiomyocytes Antioxid. Redox Signal. Lenti MR203015L2
TGFBR1 miR-140-5p alleviates the aggressive progression of Wilms' tumor through directly targeting TGFBR1 gene Cancer Manag Res Lenti TL320549
Thoc5 THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer Advanced Science Lenti RR201699L3V
TIMD4 Autophagy-related protein Vps34 controls the homeostasis and function of antigen cross-presenting CD8α(+) dendritic cells Proc. Natl. Acad. Sci. U.S.A. Lenti MR222206L1
TIMM23 Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson’s disease Cell Death & Disease Lenti RC209369L1V
Timp1 Targeting tissue inhibitor of metalloproteinase 1/2 using a shRNA lentiviral system offers a novel treatment strategy against hepatic fibrosis Int J Clin Exp Med Lenti TL712176
Timp2 Targeting tissue inhibitor of metalloproteinase 1/2 using a shRNA lentiviral system offers a novel treatment strategy against hepatic fibrosis Int J Clin Exp Med Lenti TL710553
TJP1 BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal Haematologica Lenti TL516754
TLR2 Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis Front Immunol Lenti TL320553
TLR2 Selective disruption of TLR2/MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology J. Clin. Invest. Lenti RC207597L1
TLR4 Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis Front Immunol Lenti TL320555
TLR9 Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis Front Immunol Lenti TL301076
TMEM163 Transmembrane 163 (TMEM163) protein effluxes zinc bioRxiv Lenti TL307341
TMPRSS5 Potential differences in cleavage of the S protein and type-1 interferon together control human coronavirus infection, propagation, and neuropathology within the central nervous system Journal of virology Lenti RC223774L3V
Tmx1 Characterization of Naïve and Vitamin C-Treated Mouse Schwann Cell Line MSC80: Induction of the Antioxidative Thioredoxin Related Transmembrane Protein 1. Journal of proteome research Lenti RR209795L3V
TNF Improved insulin sensitivity in obese-diabetic mice viachitosan Nanomicelles mediated silencing of pro-inflammatory Adipocytokines Nanomedicine : nanotechnology, biology, and medicine Lenti TL515379
TNF Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury J. Clin. Invest. Lenti RC206983L1
TNFRSF1A Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation Sci Signal Lenti TL308734
TNFRSF1A TNF-α receptor 1 knockdown in subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats Am. J. Physiol. Heart Circ. Physiol. Lenti TL709687
Tnfrsf21 Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6 Kidney Int. Lenti TL706747
TNS4 CTEN Induces Tumour Cell Invasion and Survival and Is Prognostic in Radiotherapy-Treated Head and Neck Cancer Cancers (Basel) 2020 Lenti TL300896
TOP2A Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations Mol. Cell Lenti TL308699
TOP2B Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations Mol. Cell Lenti TL308698
TOX TOX is a critical regulator of tumour-specific T cell differentiation Nature Lenti MR208435L2
TP53 High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression Biomed. Pharmacother. Lenti RC225604L1
TP53 ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts Oncotarget Lenti RC225604L1
TP53 Endothelial p53 Deletion Improves Angiogenesis and Prevents Cardiac Fibrosis and Heart Failure Induced by Pressure Overload in Mice J Am Heart Assoc Lenti TL320558
TPP1 A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport Cell Rep Lenti TL711322
Tpp1 Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease American Journal of Respiratory Cell and Molecular Biology Lenti RR211250L3V
TRABD2B Membrane metalloprotease TRABD2A restricts HIV-1 progeny production in resting CD4 + T cells by degrading viral Gag polyprotein. Nature immunology Lenti RC231288L1V
TRAF4 Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation J Hematol Oncol Lenti RC200345L4
TRAP1 Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia eLife Lenti TL300868V
TREX1 Accumulation of cytoplasmic DNA due to ATM deficiency activates the microglial viral response system with neurotoxic consequences J. Neurosci. Lenti TL511298
TRIM3 Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development Scand. J. Gastroenterol. Lenti RC211739L1
TRIM32 Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling Cell Death Differ. Lenti RC201289L2
TRIM32 Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling Cell Death Differ. Lenti TL308646
TRIM33 Hepatic stellate cell-specific knockout of transcriptional intermediary factor 1γ aggravates liver fibrosis J. Exp. Med. Lenti TL300849
TRIM37 TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223. Bone Lenti TL308645V
TRIM8 Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia Mol. Psychiatry Lenti TL300821V
TRIM8 TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3 Mol Oncol Lenti RC205812L2
TRIML2 Eutherian-specific gene TRIML2 attenuates inflammation in the evolution of placentation Mol. Biol. Evol. Lenti RC211281L1
TRIT1 Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer Cancers Lenti TL300819
TRP53 Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling J. Clin. Invest. Lenti MR206086L4
Trpa1 Pinosylvin Inhibits TRPA1-Induced Calcium Influx In Vitro and TRPA1-Mediated Acute Paw Inflammation In Vivo. Basic & clinical pharmacology & toxicology Lenti RR203182L3V
TRPM2 Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy Cell Death Dis Lenti TL308624
TRPM7 Isoproterenol-Dependent Activation of TRPM7 Protects Against Neurotoxin-Induced Loss of Neuroblastoma Cells Front Physiol Lenti TL320704
TRPM7 TGFβ-induced epithelial-to-mesenchymal transition in prostate cancer cells is mediated via TRPM7 expression Mol. Carcinog. Lenti TL320704
Trps1 Transcription Factor Trps1 Promotes Tubular Cell Proliferation after Ischemia-Reperfusion Injury through cAMP-Specific 3',5'-Cyclic Phosphodiesterase 4D and AKT J. Am. Soc. Nephrol Lenti TL708847
TRPV1 Capsaicin-induced Ca2+ Signaling is Enhanced via Upregulated TRPV1 Channels in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic PAH Am. J. Physiol. Lung Cell Mol. Physiol Lenti TL300807
TRPV5 Transient receptor potential vanilloid 5 (TRPV5), a highly Ca(2+) -selective TRP channel in the rat brain: relevance to neuroendocrine regulation J. Neuroendocrinol Lenti RR208885L4
TRPV6 Transient receptor potential vanilloid 5 (TRPV5), a highly Ca(2+) -selective TRP channel in the rat brain: relevance to neuroendocrine regulation J. Neuroendocrinol Lenti MR210315L4
TUBB3 Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism Molecular Therapy - Oncolytics Lenti RC200755L1V
Twist1 The emerging role of Twist proteins in hematopoietic cells and hematological malignancies Blood Cancer Journal Lenti RR200631L1V
Twist1 Vaccine-Mediated Immunotherapy Directed Against a Transcription Factor Driving the Metastatic Process Cancer Res., Feb 2014. Lenti TL308556
TXNIP Loss of TXNIP enhances peritoneal metastasis and can be abrogated by dual TORC1/2 inhibition Oncotarget Lenti TL308550
TXNRD1 Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease Free Radic. Biol. Med. Lenti TL300712
TYRO3 Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer Cancer Lett. Lenti TL316973
UAP1 Reciprocal Regulation Between O-GlcNAcylation and β-Catenin Facilitates Cell Viability and Inhibits Apoptosis in Liver Cancer DNA Cell Biol. Lenti TL308538
UBA2 Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme Cell Chem Biol Lenti RC201288L4
UBE2N The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13 Cell. Mol. Immunol. Lenti MR201092L1
Ubqln1 Enhanced Proteostasis in Post-ischemic Stroke Mouse Brains by Ubiquilin-1 Promotes Functional Recovery Cell. Mol. Neurobiol Lenti TL515928
UHRF1 UHRF1 promotes human osteosarcoma cell invasion by downregulating the expression of E-cadherin in an Rb1-dependent manner Mol Med Rep Lenti RC214251L1
Ulk1 Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research Lenti RR214983L3V
USP26 Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1\'s pro-metastatic functions in esophageal cancer Cancer Cell Int. Lenti RC223359L1V
USP7 Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) Scientific reports Lenti TL30845
VAMP3 Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1 PLoS Genet. Lenti TL515358V
VDR Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment Acta Pharmacol Sin Lenti TL320568
VGLL3 Intracellular Role for the Matrix-Modifying Enzyme Lox in Regulating Transcription Factor Subcellular Localization and Activity in Muscle Regeneration Dev. Cell Lenti MR217588L1
VHL Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression Metab. Clin. Exp. Lenti TL300577
VIM The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis PLoS Pathog. Lenti RC201546L1
VPS35 Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer’s Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein Stem Cell Repor ts Lenti TL300553
VRK2 Deletion of the Vaccinia B1 Kinase Reveals Essential Functions of this Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2 J. Virol. Lenti RC206522L1
WIF1 Wnt Signaling Drives Prostate Cancer Bone Metastatic Tropism and Invasion Transl Oncol Lenti RC205256L1
WNK1 WNK1-TAK1 signaling suppresses lipopolysaccharide-induced cytokine production and classical activation in macrophages Biochem Biophys Res Commun Lenti TL506981
WNT10A Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase Cancer Res. Lenti TL502422
WNT5A Role of Wnt5a in suppressing invasiveness of hepatocellular carcinoma via epithelial-mesenchymal transition Oncology letters Lenti TL320572
WNT5A Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis Cancer Res. Lenti TL320572V
XRCC5 Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination Nat Commun Lenti TL502435
XRN2 XRN2 promotes EMT and metastasis through regulating maturation of miR-10a Oncogene Lenti TL308334
YAP1 Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard Chemotherapy Mol. Cancer Ther. Lenti TL308332
YAP1 Corosolic acid inhibits cancer progress through inactivating YAP in hepatocellular carcinoma Oncol. Res. Lenti RC225864L3
YAP1 YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells Nat Commun Lenti TL308332
Yap1 YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells Cancer Res.2017 Lenti TL502437
YWHAZ Down-regulation of 14-3-3 zeta sensitizes human glioblastoma cells to apoptosis induction Apoptosis Lenti TL308321V
ZBP1 Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells Sci Rep Lenti TL300389
ZBTB10 The BTB Transcription Factors ZBTB11 and ZFP131 Maintain Pluripotency by Repressing Pro-Differentiation Genes SSRN Electronic Journal Lenti MR214195L4
ZBTB17 Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10. Cancer letters Lenti RC216143L4V
ZBTB17 Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1 Frontiers in Immunology Lenti RC216143L2V
ZBTB17 Miz1, a Novel Target of ING4, Can Drive Prostate Luminal Epithelial Cell Differentiation Prostate Lenti RC216143L1
ZBTB7A The miR-372-ZBTB7A Oncogenic Axis Suppresses TRAIL-R2 Associated Drug Sensitivity in Oral Carcinoma Front Oncol Lenti RC222759L2
ZDHHC15 Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation Research Square Lenti TL300350V
ZDHHC18 DHHC protein family targets different subsets of glioma stem cells in specific niches J. Exp. Clin. Cancer Res. Lenti RC209313L3
ZDHHC23 DHHC protein family targets different subsets of glioma stem cells in specific niches J. Exp. Clin. Cancer Res. Lenti RC207272L3
ZDHHC23 DHHC protein family targets different subsets of glioma stem cells in specific niches J. Exp. Clin. Cancer Res. Lenti TL300344
ZDHHC8 The palmitoyl acyltransferases ZDHHC5 and ZDHHC8 are uniquely present in DRG axons and control retrograde signaling via the Gp130/JAK/STAT3 pathway J. Biol. Chem. Lenti TL703608
Zeb1 Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2 Cellular and Molecular Gastroenterology and Hepatology Lenti TL513177V
Zeb1 Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2 Cellular and Molecular Gastroenterology and Hepatology Lenti MR223095L2V
ZEB1 Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells Nat Commun Lenti MR223095L2V
ZEB1 Knockdown of ZEB1 suppressed the formation of vasculogenic mimicry and epithelial-mesenchymal transition in the human breast cancer cell line MDA-MB-231 Mol Med Rep Lenti TL301174
ZEB1 MicroRNA-141 and MicroRNA-146b-5p Inhibit the pro-Metastatic Mesenchymal Characteristics through the RNA Binding Protein AUF1 Targeting the Transcription Factor ZEB1 and the Protein Kinase AKT J. Biol. Chem. Lenti TL301174
ZEB2 DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition Journal of Allergy and Clinical Immunology Lenti TL308288
ZEB2 A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer J. Exp. Clin. Cancer Res. Lenti RC215227L2
Zfp143 The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain Nat. Genet. Lenti TL502149
ZG16B PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway Carcinogenesis Lenti TL307561
ZIC2 ZIC2 is Essential for Maintenance of Latency and is a Target of an Immediate-Early Protein during KSHV Lytic Reactivation J. Virol. Lenti RC220798L1
ZNF746 Ovarian Cells Have Increased Proliferation in Response to Heparin-Binding Epidermal Growth Factor as Collagen Density Increases Tissue Eng Part A Lenti TR300037
ZNF746 Engineering PD-1-Presenting Platelets for Cancer Immunotherapy Nano Lett. Lenti TR300037
ZNRF3 MiR-146b-5p promotes metastasis and induces epithelial-mesenchymal transition in thyroid cancer by targeting ZNRF3. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology Lenti TL317599V