ICOS Ligand (ICOSLG) (NM_015259) Human Tagged Lenti ORF Clone
CAT#: RC208975L2
- LentiORF®
Lenti ORF clone of Human inducible T-cell co-stimulator ligand (ICOSLG), mGFP tagged
"NM_015259" in other vectors (6)
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CNY 6,000.00
Cited in 1 publication. |
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Synonyms | B7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208975).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_015259 |
ORF Size | 906 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_015259.4 |
RefSeq Size | 3320 bp |
RefSeq ORF | 909 bp |
Locus ID | 23308 |
UniProt ID | O75144 |
Protein Families | Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
MW | 33.3 kDa |
Gene Summary | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Non-immune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist
,Koh, KH;Cao, Y;Mangos, S;Tardi, NJ;Dande, RR;Lee, HW;Samelko, B;Altintas, MM;Schmitz, VP;Lee, H;Mukherjee, K;Peev, V;Cimbaluk, DJ;Reiser, J;Hahm, E;,
J. Clin. Invest.
,PubMed ID 30747722
[ICOSLG]
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Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208975 | ICOSLG (Myc-DDK-tagged)-Human inducible T-cell co-stimulator ligand (ICOSLG) |
CNY 3,600.00 |
|
RC208975L1 | Lenti ORF clone of Human inducible T-cell co-stimulator ligand (ICOSLG), Myc-DDK-tagged |
CNY 6,000.00 |
|
RC208975L3 | Lenti ORF clone of Human inducible T-cell co-stimulator ligand (ICOSLG), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC208975L4 | Lenti ORF clone of Human inducible T-cell co-stimulator ligand (ICOSLG), mGFP tagged |
CNY 5,890.00 |
|
RG208975 | ICOSLG (tGFP-tagged) - Human inducible T-cell co-stimulator ligand (ICOSLG) |
CNY 5,200.00 |
|
SC309183 | ICOSLG (untagged)-Human inducible T-cell co-stimulator ligand (ICOSLG) |
CNY 3,600.00 |
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