Noxo1 (NM_027988) Mouse Tagged Lenti ORF Clone
CAT#: MR205276L1
- LentiORF®
Lenti ORF clone of Noxo1 (Myc-DDK-tagged) - Mouse NADPH oxidase organizer 1 (Noxo1)
"NM_027988" in other vectors (5)
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CNY 7,888.00
Cited in 1 publication. |
CNY 600.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | 2310034C04Rik; hslt; P41NOX; P41NOXA; P41NOXB; P41NOXC; Snx28 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR205276).
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Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_027988 |
ORF Size | 1050 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_027988.4, NP_082264.2 |
RefSeq Size | 2239 bp |
RefSeq ORF | 1050 bp |
Locus ID | 71893 |
UniProt ID | Q8VCM2 |
Gene Summary | Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD
,Seimetz, M;Sommer, N;Bednorz, M;Pak, O;Veith, C;Hadzic, S;Gredic, M;Parajuli, N;Kojonazarov, B;Kraut, S;Wilhelm, J;Knoepp, F;Henneke, I;Pichl, A;Kanbagli, Z;Scheibe, S;Fysikopoulos, A;Wu, C;Klepetko, W;Jaksch, P;Eichstaedt, C;Grünig, E;Hinderhofer, K;Geiszt, M;Müller, N;Rezende, F;Buchmann, G;Wittig, I;Hecker, M;Hecker, A;Padberg, W;Dorfmüller, P;Gattenlöhner, S;Vogelmeier, C;Günther, A;Karnati, S;Baumgart-Vogt, E;Schermuly, R;Ghofrani, H;Seeger, W;Schröder, K;Grimminger, F;Brandes, R;Weissmann, N;,
Nat Metab
,PubMed ID 32694733
[NOXO1]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC207709 | Noxo1 (untagged) - Mouse NADPH oxidase organizer 1 (Noxo1), (10ug) |
CNY 5,488.00 |
|
MR205276 | Noxo1 (Myc-DDK-tagged) - Mouse NADPH oxidase organizer 1 (Noxo1) |
CNY 5,488.00 |
|
MR205276L2 | Lenti ORF clone of Noxo1 (mGFP-tagged) - Mouse NADPH oxidase organizer 1 (Noxo1) |
CNY 5,890.00 |
|
MR205276L3 | Lenti ORF clone of Noxo1 (Myc-DDK-tagged) - Mouse NADPH oxidase organizer 1 (Noxo1) |
CNY 5,890.00 |
|
MR205276L4 | Lenti ORF clone of Noxo1 (mGFP-tagged) - Mouse NADPH oxidase organizer 1 (Noxo1) |
CNY 5,890.00 |