Dnmt2 (TRDMT1) Human Gene Knockout Kit (CRISPR)

CAT#: KN208363BN

TRDMT1 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


TRDMT1 mouse monoclonal antibody,clone OTI8H10
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TRDMT1 (Myc-DDK-tagged)-Human tRNA aspartic acid methyltransferase 1 (TRDMT1)
    • 10 ug

CNY 3,656.00
CNY 3,990.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Dnmt2
Locus ID 1787
Kit Components

KN208363G1, Dnmt2 gRNA vector 1 in pCas-Guide CRISPR vector

KN208363G2, Dnmt2 gRNA vector 2 in pCas-Guide CRISPR vector

KN208363BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004412, NM_176081, NM_176083, NM_176084, NM_176085, NM_176086, NM_001321006, NM_001321007, NM_001351219, NM_001351220, NM_001351221, NM_001351222, NM_001351223
Synonyms DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
Summary This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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