Human Dnmt2 (TRDMT1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRDMT1
Locus ID	1787
Kit Components	GA101243G1, Dnmt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101243G2, Dnmt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101243G3, Dnmt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_004412, NM_176081, NM_176083, NM_176084, NM_176085, NM_176086, NM_001321006, NM_001321007, NM_001351219, NM_001351220, NM_001351221, NM_001351222, NM_001351223
Synonyms	DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
Summary	This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]

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