Mouse Mybbp1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mybbp1a
Locus ID	18432
Kit Components	GA203075G1, Mybbp1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203075G2, Mybbp1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203075G3, Mybbp1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016776
Synonyms	AL024407; AU019902; p67MBP; P160; p160MBP
Summary	May activate or repress transcription via interactions with sequence specific DNA-binding proteins (PubMed:9447996, PubMed:11956195, PubMed:14744933). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (PubMed:14744933). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (PubMed:19129230). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (PubMed:19129230). Has a role in rRNA biogenesis together with PWP1 (By similarity).[UniProtKB/Swiss-Prot Function]

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