Human UNC13B activation kit by CRISPRa

CAT#: GA107171

UNC13B CRISPRa kit - CRISPR gene activation of human unc-13 homolog B



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal antibody to UNC13B (unc-13 homolog B (C. elegans))
    • 100 ul

CNY 6,281.00


UNC13B (Myc-DDK-tagged)-Human unc-13 homolog B (C. elegans) (UNC13B)
    • 10 ug

CNY 10,888.00


UNC13B Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol UNC13B
Locus ID 10497
Kit Components

GA107171G1, UNC13B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107171G2, UNC13B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107171G3, UNC13B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_006377, NM_001330653
Synonyms MUNC13; UNC13; Unc13h2
Summary This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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