UNC13B Rabbit Polyclonal Antibody
CAT#: TA308990
Rabbit Polyclonal antibody to UNC13B (unc-13 homolog B (C. elegans))
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CNY 6,281.00
货期*
5周
规格
Cited in 1 publication. |
经常一起买 (1)
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000 |
Reactivity | Human, Mouse, Rat, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 680 and 957 of UNC13B (Uniprot ID#O14795) |
Formulation | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 181 kDa |
Gene Name | unc-13 homolog B (C. elegans) |
Database Link | |
Background | This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq] |
Synonyms | MUNC13; UNC13; Unc13h2 |
Note | Seq homology of immunogen across species: Mouse (99%), Rat (98%), Bovine (99%) |
Reference Data | |
Protein Families | Druggable Genome |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons
,Liang, D;Xue, Z;Xue, J;Xie, D;Xiong, K;Zhou, H;Zhang, F;Su, X;Wang, G;Zou, Q;Liu, Y;Yang, J;Ma, H;Peng, L;Zeng, C;Li, G;Wang, L;Chen, YH;,
Protein & cell
,PubMed ID 33548033
[UNC13B]
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