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Amer1 (NM_175179) Mouse Untagged Clone
CAT＃: MC223690
Amer1 (untagged) - Mouse family with sequence similarity 123, member B (Fam123b), (10ug)
CNY 14,540.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2810002O09Rik; AW492303; Fam123b; Wtx |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223690 representing NM_175179
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGAGTCAACAGGATGAAGCTGTTCAAACCAAAGGAGCATCAACTTCTAGCGATGCCCAAGACCAGG GAGCTGAAAAGGGAGCCAAGAATAAGACAACTGAGGCAACAGAAGGACCAACATCAGAGCCTCCCTTATC AGGCCCAGGTAGGCTGAAGAAAACTGCCATGAAACTCTTTGGTGGCAAGAAGGGAATCTGTACTCTGCCT AGTTTCTTTGGGGGTGGACGAAGCAAAGGTTCTGGGAAAGTCAGCTCTAAGAAAAGTCTAAACAAGAGTA AGACTCACGATGGTCTAAGTGAAGCGTCTCAGGGACCTGAAGATGTTGTCATTGAAGAAACAGACCTCTC TACACCTTTGTCCAAGTCATCTGCTCAATTTCCTAGCTCCCAGAGTGCCAATGGAGCGTTGGAGATAGGC TCTAAACATAAGACATCTGGGACTGAAGCCATAGAAAAAGCTGGAGTTGAGAAGGTACCCTCTGTGCACA AGCCGAAGAAAAGCCTAAAAAGCTTCTTTAGCAGTATCCGCCGTCACCGGAAGGGCAAGACTTCTGGGGC TGACCAAAGTGTGCCAGGGGCCAAGGAACTTGAGGGGGCAAGAACCAGGTCTCATGAGCATGTGAGTTCA ATCTCTCTGCCCAGCTCTGAGGAGATATTCCGAGACACTAGAAAGGAAAATGCCAAACCCCAGGATGCCC CTGGACCAAAAATGTCTCCAGCACAAGTACATTTTTCACCAACTACTGAGAAGGCAGCTTGTAAAAATCC AGAAAAACTCACAAGGACCTGTGCCTCAGAGTTCATGCAGCCCAAGCCTGTTCTTGAAGGTGGTAGTCTA GAGGAGCCCCACACTTCAGAAACAGAAGGAAAAGTGGTGGCAGGAGAAGTAAACCCACCCAATGGCCCTG TTGGGGATCAGCTAAGCCTCTTGTTTGGGGATGTTACATCGCTAAAAAGCTTTGACTCACTGACAGGTTG TGGTGACATTATAGCAGAACAGGACATGGACAGCATGACAGATAGCATGGCCTCTGGTGGCCAGAGGGCC AACCGAGATGGGACCAAGCGAAGTTCCTGCTTGGTAACCTACCAAGGAGGTGGGGAGGAGATGGCCTTGC CAGATGATGATGACAATGATGATGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGA AGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAATTATTAGAGGATGAAGAGGAGGTTAAGGATGGA GAGGAAAATGATGACTTAGAGTATCTGTGGGCAAGTGCCCAGATATACCCAAGATTTAATATGAATCTGG GCTACCATACTGCTATATCTCCCAGCCACCAGGGCTACATGCTTCTTGACCCAGTTCAGTCTTATCCTAA TCTAGGCCTTGGAGAACTTTTGACACCTCAGAGCGACCAGCAAGAGTCTGCTCCCAATAGTGATGAAGGT TATTATGACTCTACCACACCAGGATTTGAGGATGATTCAGGTGAGGCTCTGGGACTTGCCCACAGGGATT GTCTACCCAGGGACAGCTATAGTGGTGATGCGCTATATGAGTTCTATGAGCCAGATGACAGTCTTGAGCA CTCCCCACCTGGGGATGACTGCCTATATGACCTCCGTGGACGCAACTCAGAGATGTTGGATCCTTTCTTG AACTTGGAGCCCTTTTCTTCTCGGCCACCTGGGGCAATGGAAACCGAGGAAGAACGGCTAGTGACCATCC AGAAGCAGTTGCTATACTGGGAACTTCGCCGGGAGCAGCGTGAGGCTCAAGAGGCATGTGCCAGAGAGGC TCATGCCAGAGAAGCTTATGCCCGAGACACCCATACTCGGGAATCTTATGGCAGAAATGTCCGAGCCCGA GAAACTCAGGCCTTAGAGGCTCATTCTCAAGAGGGTCGAGTCCAAGAGACCAAGGTACGGCAGGAGAAGC CTGCCTTGGAGTATCAGATGAGGCCCTTAGGTCCCTCAGTGATGGGTCTGGTGGCAGGGACATCAGGAGG TTCTCAGACTTCTCACCGGGGAACCACTTCAGCTTTCCCTGCTACTTCTAGCAGTGAGCCAGACTGGAGG GATTTCCGTCCTCTGGAGAAGCGTTTTGAGGGGACTTGTTCCAAAAAAGATCAAAGTACTTGTTTAATGC AGCTCTTCCAGAGTGATGCCATGTTTGAGCCAGACATGCAAGAAGCAAATTTTGGAGGCTCACCCAGGAA GGCGTACCCTAGTTACTCACCCCCTGAGGAGCCAGAGGAAGAAGAAGAGGAGAAGGAAGGGAATGCCACT GTGAGTTTCTCACAGGCCCTAGTAGAGTTCACCAGCAATGGAAACCTTTTTACCAGCATGTCCTACAGCT CTGATTCTGACTCATCCTTCACTCAAAACCTCCCTGAGCTGCCCCCCATGGTCACCTTTGATATTGCTGA CGTGGAACGAGATGGAGAAGGCAAGTGTGAAGAGAATCCTGAGTTCAACAATGACGAAGATCTTACAGCC TCCTTGGAAGCTTTTGAGCTGGGTTATTACCACAAACATGCCTTCAACAGCTATCACAGTCGGTTCTACC AAGGCCTGCCCTGGGGAGTTAGCAGCCTCCCTCGATACTTAGGACTCCCCGGAGTCCACCCTCGACCTCC TCCTGCTGCAATGGCACTCAATAGGAGAAGCCGTTCCCTTGACAATGCAGAGTCTCTGGAGCTGGAGCTC TCCAGTTCTCACCTAGCCCAGGGTTACATGGAGTCTGATGAGCTCCAGGCCCACCAGGAAGATTCAGATG AAGAAGGTGAAGAAGAGGAAGGAGAATGGGGTCGGGATAGTCCCTTGTCTCTCTACACTGAACCTCCAGG GGTCTATGACTGGCCTCCCTGGGCTCACTGTCCTCTTCCAGTGGGGCCAGGTCTTGCTTGGATGAGCCCT AATCAGTTGTATGAGCCTTTCAATCAGTCTTCCTATGTGCAGGCAACCTGTTGTGTACCTCCTGTGGCAA TGCCAGTGTCAGTGCCAGGAAGAACACCTGGAGACTCTGTGTCTCAGCTAGCTCGACCTTCGCACCTACC CCTGCCCATGGGCCCTTGCTATAACCTTCAATCACAGGCCTCCCAGAGTGGGAGGGCCAAGCCTCGGGAT GTACTGCTGCCTGTAGATGAGCCCAGTTGCTCTTCCATTTCTGGAGCCAACTCTCAGTCTCAAGCCAAGC CTGTAGGTATCACCCATGGTATCCCTCAGCTGCCCAGGGTGCGGCCTGAACCCTTCCAGCTTCAACCCAA TCACTATCGAGCTTCCAACCTTGACCTGTCAAAGGAGAGGGGTGAGCAAGGTGCCTCTCTCTCTACCAGC TACTCCTCTACTGCCATGAATGGAAACCTAGCCAAGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_175179 |
| Insert Size | 3399 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175179.4, NP_780388.2 |
| RefSeq Size | 8476 bp |
| RefSeq ORF | 3399 bp |
| Locus ID | 72345 |
| UniProt ID | Q7TS75 |
| Gene Summary | Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222769 | Amer1 (tGFP-tagged) - Mouse family with sequence similarity 123 member B (Fam123b), (10ug) |
CNY 9,220.00 |
|
| MR222769 | Amer1 (Myc-DDK-tagged) - Mouse family with sequence similarity 123, member B (Fam123b) |
CNY 8,672.00 |
|
| MR222769L3 | Lenti ORF clone of Amer1 (Myc-DDK-tagged) - Mouse family with sequence similarity 123, member B (Fam123b) |
CNY 10,260.00 |
|
| MR222769L4 | Lenti ORF clone of Amer1 (mGFP-tagged) - Mouse family with sequence similarity 123, member B (Fam123b) |
CNY 10,260.00 |
