Amer1 (NM_175179) Mouse Tagged Lenti ORF Clone
CAT#: MR222769L4
- LentiORF®
Lenti ORF clone of Amer1 (mGFP-tagged) - Mouse family with sequence similarity 123, member B (Fam123b)
"NM_175179" in other vectors (4)
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CNY 10,260.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Synonyms | 2810002O09Rik; AW492303; Fam123b; Wtx |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222769).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_175179 |
ORF Size | 3396 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_175179.4, NP_780388.2 |
RefSeq Size | 8476 bp |
RefSeq ORF | 3399 bp |
Locus ID | 72345 |
UniProt ID | Q7TS75 |
Gene Summary | Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC223690 | Amer1 (untagged) - Mouse family with sequence similarity 123, member B (Fam123b), (10ug) |
CNY 14,540.00 |
|
MG222769 | Amer1 (tGFP-tagged) - Mouse family with sequence similarity 123 member B (Fam123b), (10ug) |
CNY 9,220.00 |
|
MR222769 | Amer1 (Myc-DDK-tagged) - Mouse family with sequence similarity 123, member B (Fam123b) |
CNY 8,672.00 |
|
MR222769L3 | Lenti ORF clone of Amer1 (Myc-DDK-tagged) - Mouse family with sequence similarity 123, member B (Fam123b) |
CNY 10,260.00 |