SCP3 (SYCP3) Human shRNA Plasmid Kit (Locus ID 50511)

Specifications

Product Data
Product Name	SCP3 (SYCP3) Human shRNA Plasmid Kit (Locus ID 50511)
Locus ID	50511
UniProt ID	Q8IZU3
Synonyms	COR1; RPRGL4; SCP3; SPGF4
Vector	pGFP-C-shLenti
Format	Lentiviral plasmids
Kit Components	SYCP3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 50511). 5µg purified plasmid DNA per construct 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq	NM_001177948, NM_001177949, NM_153694, NM_153694.1, NM_153694.2, NM_153694.3, NM_153694.4, NM_001177949.1, NM_001177948.1, BC062662, BC062662.1, NM_001177949.2
Summary	This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010]
shRNA Design	These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed	OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.