HIP1 Human shRNA Lentiviral Particle (Locus ID 3092)

Specifications

Product Data
Product Name	HIP1 Human shRNA Lentiviral Particle (Locus ID 3092)
Locus ID	3092
Synonyms	HIP-I; ILWEQ; SHON; SHONbeta; SHONgamma
Vector	pGFP-C-shLenti
Format	Lentiviral particles
RefSeq	NM_001243198, NM_005338, NM_005338.2, NM_005338.3, NM_005338.4, NM_005338.5, NM_005338.6, NM_001243198.1, NM_001243198.2, BC110545, BC082970, BC139786, BM550560, BM556334, BM739599, NM_005338.7, NM_001243198.3
Summary	The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
shRNA Design	These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed	OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.