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IL1RA (IL1RN) (NM_000577) Human Recombinant Protein
CAT＃: TP720025
Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3
View other "IL1RA" proteins (15)
|
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CNY 3,140.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
Arg26-Glu177
|
| Tag | Tag Free |
| Predicted MW | 17.3 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Lyophilized from a 0.2 um filtered solution of PBS,PH7.4. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
| Bioactivity | ED50 is 0.5 ng/ml as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells. Specific Activity of 2.0 x 106 IU/mg. |
| Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
| Reference Data | |
| RefSeq | NP_000568 |
| Locus ID | 3557 |
| UniProt ID | P18510 |
| Cytogenetics | 2q14.1 |
| Synonyms | DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4 |
| Summary | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] |
| Protein Families | Druggable Genome, Secreted Protein |
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| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403570 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC403571 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC406440 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC424628 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403570 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 1 |
CNY 3,080.00 |
|
| LY403571 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 4 |
CNY 3,080.00 |
|
| LY406440 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 2 |
CNY 3,080.00 |
|
| LY424628 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
CNY 3,080.00 |
|
| PH302447 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776215) |
CNY 14,250.00 |
|
| PH312460 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568) |
CNY 19,520.00 |
|
| PH318518 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776214) |
CNY 19,520.00 |
|
| TP302447 | Purified recombinant protein of Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, 20 µg |
CNY 2,900.00 |
|
| TP312460 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3, 20 µg |
CNY 2,900.00 |
|
| TP318518 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP760033 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2,040.00 |
