IL1RA (IL1RN) (NM_000577) Human Mass Spec Standard

CAT#: PH312460

IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212460
Predicted MW 17.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000568
RefSeq Size 1802
RefSeq ORF 477
Synonyms DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
Locus ID 3557
Cytogenetics 2q14.1
Summary The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, Secreted Protein
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