WDR79 (WRAP53) (NM_001143990) Human Mass Spec Standard

CAT#: PH327755

WRAP53 MS Standard C13 and N15-labeled recombinant protein (NP_001137462)



  View other "WDR79" proteins (15)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description WRAP53 MS Standard C13 and N15-labeled recombinant protein (NP_001137462)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC227755
Predicted MW 59.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001137462
RefSeq ORF 1644
Synonyms DKCB3; TCAB1; WDR79
Locus ID 55135
Cytogenetics 17p13.1
Summary This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]
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