PAICS (NM_006452) Human Mass Spec Standard

CAT#: PH315225

PAICS MS Standard C13 and N15-labeled recombinant protein (NP_006443)



  View other "PAICS" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2
    • 100 ug

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Anti-PAICS mouse monoclonal antibody, clone OTI2C9 (formerly 2C9)
    • 100 ul

CNY 1,999.00
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Specifications

Product Data
Description PAICS MS Standard C13 and N15-labeled recombinant protein (NP_006443)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215225
Predicted MW 47.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006443
RefSeq Size 3350
RefSeq ORF 1275
Synonyms ADE2; ADE2H1; AIRC; PAIS
Locus ID 10606
Cytogenetics 4q12
Summary This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Purine metabolism
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