HMGN3 (NM_004242) Human Mass Spec Standard

Specifications

Product Data
Description	HMGN3 MS Standard C13 and N15-labeled recombinant protein (NP_004233)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC213403
Predicted MW	10.5 kDa
Protein Sequence	Sequence Link (showhide) >RC213403 representing NM_004242 Red=Cloning site Green=Tags(s) MPKRKSPENTEGKDGSKVTKQEPTRRSARLSAKPAPPKPEPKPRKTSAKKEPGAKISRGAKGKKEEKQEA GKEGTAPSENGETKAEEAQKTESVDNEGE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004233
RefSeq Size	935
RefSeq ORF	297
Synonyms	PNAS-24; PNAS-25; TRIP7
Locus ID	9324
Cytogenetics	6q14.1
Summary	The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]
Protein Families	Druggable Genome

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