Oncostatin M (OSM) (NM_020530) Human Mass Spec Standard

CAT#: PH304277

OSM MS Standard C13 and N15-labeled recombinant protein (NP_065391)



  View other "Oncostatin M" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description OSM MS Standard C13 and N15-labeled recombinant protein (NP_065391)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204277
Predicted MW 28.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_065391
RefSeq Size 1869
RefSeq ORF 756
Locus ID 5008
Cytogenetics 22q12.2
Summary This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
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