Oncostatin M (OSM) (NM_020530) Human Recombinant Protein
CAT#: TP720609
Purified recombinant protein of Human oncostatin M (OSM)
View other "Oncostatin M" proteins (5)
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CNY 3,140.00
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CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Ala26-Arg221
|
Tag | N-His |
Predicted MW | 24.4 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mMTris-HCl,1mMEDTA,200mMNaCl,pH7.5. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_065391 |
Locus ID | 5008 |
UniProt ID | P13725 |
Refseq Size | 1869 |
Cytogenetics | 22q12.2 |
Refseq ORF | 756 |
Summary | This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC412433 | OSM HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY412433 | Transient overexpression lysate of oncostatin M (OSM) |
CNY 3,080.00 |
|
PH304277 | OSM MS Standard C13 and N15-labeled recombinant protein (NP_065391) |
CNY 19,520.00 |
|
TP304277 | Recombinant protein of human oncostatin M (OSM), 20 µg |
CNY 2,900.00 |
|
TP750016 | Recombinant protein of human Oncostatin M (OSM) produced in E. coli. |
CNY 4,020.00 |
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