Serum Amyloid A (SAA1) (NM_199161) Human Mass Spec Standard

CAT#: PH302738

SAA1 MS Standard C13 and N15-labeled recombinant protein (NP_954630)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description SAA1 MS Standard C13 and N15-labeled recombinant protein (NP_954630)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202738
Predicted MW 13.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_954630
RefSeq Size 531
RefSeq ORF 366
Synonyms PIG4; SAA; SAA2; TP53I4
Locus ID 6288
Cytogenetics 11p15.1
Summary This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Jul 2020]
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