FAM178A (SLF2) Human Gene Knockout Kit (CRISPR)
CAT#: KN224540RB
FAM178A - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | FAM178A |
Locus ID | 55719 |
Kit Components |
KN224540G1, FAM178A gRNA vector 1 in pCas-Guide CRISPR vector KN224540G2, FAM178A gRNA vector 2 in pCas-Guide CRISPR vector KN224540RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001136123, NM_001243770, NM_018121, NM_144592, NR_024245 |
Synonyms | C10orf6; FAM178A |
Summary | Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN224540 | SLF2 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN224540BN | FAM178A - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN224540LP | FAM178A - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN424540 | FAM178A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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GA110910 | SLF2 CRISPRa kit - CRISPR gene activation of human SMC5-SMC6 complex localization factor 2 |
CNY 12,255.00 |
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