Human FAM178A (SLF2) activation kit by CRISPRa
CAT#: GA110910
SLF2 CRISPRa kit - CRISPR gene activation of human SMC5-SMC6 complex localization factor 2
CNY 12,255.00
CNY 8,256.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SLF2 |
Locus ID | 55719 |
Kit Components | GA110910G1, FAM178A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110910G2, FAM178A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110910G3, FAM178A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001136123, NM_001243770, NM_018121, NM_144592, NR_024245 |
Synonyms | C10orf6; FAM178A |
Summary | Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN224540 | SLF2 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN224540BN | FAM178A - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN224540LP | FAM178A - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN224540RB | FAM178A - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN424540 | FAM178A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |