SLC30A10 Human Gene Knockout Kit (CRISPR)

CAT#: KN220219RB

SLC30A10 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

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CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (2)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


SLC30A10 (Myc-DDK-tagged)-Human solute carrier family 30, member 10 (SLC30A10)
    • 10 ug

CNY 3,656.00
CNY 4,280.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol SLC30A10
Locus ID 55532
Kit Components

KN220219G1, SLC30A10 gRNA vector 1 in pCas-Guide CRISPR vector

KN220219G2, SLC30A10 gRNA vector 2 in pCas-Guide CRISPR vector

KN220219RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001004433, NM_018713, NR_046437
Synonyms DKFZp547M236; solute carrier family 30 (zinc transporter), member 10; solute carrier family 30, member 10; zinc transporter 8; ZnT-10; ZNT8; ZNT8, ZnT-10, DKFZp547M236; ZNT10; ZRC1
Summary This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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