Human SLC30A10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC30A10
Locus ID	55532
Kit Components	GA110780G1, SLC30A10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110780G2, SLC30A10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110780G3, SLC30A10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001004433, NM_018713, NR_046437
Synonyms	DKFZp547M236; solute carrier family 30 (zinc transporter), member 10; solute carrier family 30, member 10; zinc transporter 8; ZnT-10; ZNT8; ZNT8, ZnT-10, DKFZp547M236; ZNT10; ZRC1
Summary	This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]

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