Acid sphingomyelinase (SMPD1) Human Gene Knockout Kit (CRISPR)
CAT#: KN219758BN
SMPD1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 1,999.00
CNY 2,700.00
CNY 4,696.00
CNY 7,410.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | Acid sphingomyelinase |
Locus ID | 6609 |
Kit Components |
KN219758G1, Acid sphingomyelinase gRNA vector 1 in pCas-Guide CRISPR vector KN219758G2, Acid sphingomyelinase gRNA vector 2 in pCas-Guide CRISPR vector KN219758BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000543, NM_001007593, NM_001318087, NM_001318088, NR_027400, NR_134502, NM_001365135 |
Synonyms | ASM; ASMASE; NPD |
Summary | The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN219758 | SMPD1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN219758LP | SMPD1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN219758RB | SMPD1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN419758 | SMPD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA104522 | SMPD1 CRISPRa kit - CRISPR gene activation of human sphingomyelin phosphodiesterase 1 |
CNY 12,255.00 |
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