Fukutin (FKTN) Human Gene Knockout Kit (CRISPR)

CAT#: KN211422BN

FKTN - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit Polyclonal antibody to Fukutin (fukutin)
    • 100 ul

CNY 6,281.00


FKTN (Myc-DDK-tagged)-Human fukutin (FKTN), transcript variant 1
    • 10 ug

CNY 3,656.00
CNY 3,990.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Fukutin
Locus ID 2218
Kit Components

KN211422G1, Fukutin gRNA vector 1 in pCas-Guide CRISPR vector

KN211422G2, Fukutin gRNA vector 2 in pCas-Guide CRISPR vector

KN211422BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001079802, NM_001198963, NM_006731, NM_001351496, NM_001351497, NM_001351498, NM_001351499, NM_001351500, NM_001351501, NM_001351502, NR_147213, NR_147214
Synonyms CMD1X; FCMD; LGMD2M; MDDGA4; MDDGB4; MDDGC4
Summary The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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