Human Fukutin (FKTN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FKTN
Locus ID	2218
Kit Components	GA101554G1, Fukutin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101554G2, Fukutin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101554G3, Fukutin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001079802, NM_001198963, NM_006731, NM_001351496, NM_001351497, NM_001351498, NM_001351499, NM_001351500, NM_001351501, NM_001351502, NR_147213, NR_147214
Synonyms	CMD1X; FCMD; LGMD2M; MDDGA4; MDDGB4; MDDGC4
Summary	The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2010]

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