NRAS Human Gene Knockout Kit (CRISPR)
CAT#: KN202681RB
NRAS - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 1,999.00
CNY 2,700.00
CNY 3,600.00
CNY 3,705.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | NRAS |
Locus ID | 4893 |
Kit Components |
KN202681G1, NRAS gRNA vector 1 in pCas-Guide CRISPR vector KN202681G2, NRAS gRNA vector 2 in pCas-Guide CRISPR vector KN202681RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_002524 |
Synonyms | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 |
Summary | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
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KN202681 | NRAS - human gene knockout kit via CRISPR, HDR mediated |
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KN202681BN | NRAS - human gene knockout kit via CRISPR, HDR mediated |
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KN202681LP | NRAS - human gene knockout kit via CRISPR, HDR mediated |
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