Human NRAS activation kit by CRISPRa

CAT#: GA103268

NRAS CRISPRa kit - CRISPR gene activation of human NRAS proto-oncogene, GTPase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
NRAS mouse monoclonal antibody, clone OTI5G7 (formerly 5G7)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


NRAS (Myc-DDK-tagged)-Human neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS)
    • 10 ug

CNY 3,600.00
CNY 3,705.00


Rabbit Polyclonal NRAS Antibody
    • 100 ug

CNY 5,302.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol NRAS
Locus ID 4893
Kit Components

GA103268G1, NRAS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103268G2, NRAS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103268G3, NRAS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002524
Synonyms ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6
Summary This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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