Sigma1 receptor (SIGMAR1) Human Gene Knockout Kit (CRISPR)
CAT#: KN201206LP
SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 2,400.00
CNY 3,705.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Sigma1 receptor |
Locus ID | 10280 |
Kit Components |
KN201206G1, Sigma1 receptor gRNA vector 1 in pCas-Guide CRISPR vector KN201206G2, Sigma1 receptor gRNA vector 2 in pCas-Guide CRISPR vector KN201206LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001282205, NM_001282206, NM_001282207, NM_001282208, NM_001282209, NM_005866, NM_147157, NM_147158, NM_147159, NM_147160, NR_104108 |
Synonyms | ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP |
Summary | This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN201206 | SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN201206BN | SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN201206RB | SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN401206 | SIGMAR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA107002 | SIGMAR1 CRISPRa kit - CRISPR gene activation of human sigma non-opioid intracellular receptor 1 |
CNY 12,255.00 |
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