MCL1 Human Gene Knockout Kit (CRISPR)
CAT#: KN200521RB
MCL1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 1,999.00
CNY 2,700.00
CNY 5,488.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | MCL1 |
Locus ID | 4170 |
Kit Components |
KN200521G1, MCL1 gRNA vector 1 in pCas-Guide CRISPR vector KN200521G2, MCL1 gRNA vector 2 in pCas-Guide CRISPR vector KN200521RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001197320, NM_021960, NM_182763 |
Synonyms | bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM |
Summary | This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN200521 | MCL1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN200521BN | MCL1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN200521LP | MCL1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN400521 | MCL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA102843 | MCL1 CRISPRa kit - CRISPR gene activation of human MCL1 apoptosis regulator, BCL2 family member |
CNY 12,255.00 |