Human MCL1 activation kit by CRISPRa

CAT#: GA102843

MCL1 CRISPRa kit - CRISPR gene activation of human MCL1 apoptosis regulator, BCL2 family member



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Anti-MCL1 mouse monoclonal antibody, clone OTI10F6 (formerly 10F6)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


MCL1 (Myc-DDK-tagged)-Human myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 10 ug

CNY 5,488.00


Anti-MCL1 mouse monoclonal antibody, clone OTI10F6 (formerly 10F6)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MCL1
Locus ID 4170
Kit Components

GA102843G1, MCL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102843G2, MCL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102843G3, MCL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001197320, NM_021960, NM_182763
Synonyms bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
Summary This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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