SATB1 Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	SATB1
Locus ID	6304
Kit Components	KN200421G1, SATB1 gRNA vector 1 in pCas-Guide CRISPR vector KN200421G2, SATB1 gRNA vector 2 in pCas-Guide CRISPR vector KN200421BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Reference Data
RefSeq	NM_001131010, NM_001195470, NM_002971, NM_001322871, NM_001322872, NM_001322873, NM_001322874, NM_001322875, NM_001322876
Synonyms	DNA-binding protein SATB1; SATB homeobox 1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)
Summary	This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016]

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