Human SATB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SATB1
Locus ID	6304
Kit Components	GA104278G1, SATB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104278G2, SATB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104278G3, SATB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001131010, NM_001195470, NM_002971, NM_001322871, NM_001322872, NM_001322873, NM_001322874, NM_001322875, NM_001322876
Synonyms	DNA-binding protein SATB1; SATB homeobox 1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)
Summary	This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016]

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