Mouse Oprl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Oprl1
Locus ID	18389
Kit Components	GA203051G1, Oprl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203051G2, Oprl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203051G3, Oprl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252565, NM_011012, NR_045540, NR_045541, NR_045542, NR_134926
Synonyms	KOR-3; KOR3; LC132; MOR-C; morc; NOP; Oprl; ORGC; ORL1; XOR1
Summary	The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

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