Mouse Kcnj15 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnj15
Locus ID	16516
Kit Components	GA202266G1, Kcnj15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202266G2, Kcnj15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202266G3, Kcnj15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039056, NM_001039057, NM_001271687, NM_001271689, NM_001271690, NM_001271691, NM_001271692, NM_001271693, NM_001271694, NM_001271695, NM_019664, NR_073406
Synonyms	4930414N08Rik; AI182284; AI267127; IRKK; Kir4.2
Summary	Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.[UniProtKB/Swiss-Prot Function]

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