Human CSPP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CSPP1
Locus ID	79848
Kit Components	GA112676G1, CSPP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112676G2, CSPP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112676G3, CSPP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001077204, NM_001291339, NM_024790, NM_001363132, NM_001363131, NM_001363133, NM_001364869, NM_001364870
Synonyms	centrosome and spindle pole associated protein 1; centrosome spindle pole associated protein; centrosome spindle pole associated protein 1; CSPP; FLJ22490; FLJ38886
Summary	This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

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