Human NGLY1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NGLY1
Locus ID	55768
Kit Components	GA110953G1, NGLY1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110953G2, NGLY1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110953G3, NGLY1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145293, NM_001145294, NM_001145295, NM_018297
Synonyms	CDDG; CDG1V; PNG1; PNGase
Summary	This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]

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