Human REV1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	REV1
Locus ID	51455
Kit Components	GA109816G1, REV1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109816G2, REV1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109816G3, REV1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001037872, NM_001321454, NM_001321455, NM_001321458, NM_001321459, NM_001321460, NM_016316, NR_135649, NR_135650, NR_135651, NR_135652, NR_135653
Synonyms	AIBP80; REV1L
Summary	This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]

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