REV1 Mouse Monoclonal Antibody [Clone ID: OTI1E12]

Specifications

Product Data
Clone Name	OTI1E12
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1079-1251 of human REV1 (NP_057400) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	REV1, DNA directed polymerase
Database Link	NP_057400 Entrez Gene 316344 RatEntrez Gene 51455 Human UniProt ID Q9UBZ9
Background	This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]
Synonyms	AIBP80; REV1L
Reference Data
Protein Families	Druggable Genome

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