Human Nesprin 2 (SYNE2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SYNE2
Locus ID	23224
Kit Components	GA108140G1, Nesprin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108140G2, Nesprin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108140G3, Nesprin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_015180, NM_182910, NM_182912, NM_182913, NM_182914
Synonyms	EDMD5; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; TROPH
Summary	The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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