Human DNA Polymerase iota (POLI) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POLI
Locus ID	11201
Kit Components	GA107719G1, DNA Polymerase iota gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107719G2, DNA Polymerase iota gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107719G3, DNA Polymerase iota gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_007195, NM_001351610, NM_001351611, NM_001351612, NM_001351613, NM_001351614, NM_001351615, NM_001351616, NM_001351617, NM_001351618, NM_001351619, NM_001351620, NM_001351621, NM_001351632, NR_147257
Synonyms	RAD3OB; RAD30B
Summary	The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.