Human Apg12 (ATG12) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATG12
Locus ID	9140
Kit Components	GA106092G1, Apg12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106092G2, Apg12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106092G3, Apg12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001277783, NM_004707, NR_033362, NR_033363, NR_073603, NR_073604, NR_073605
Synonyms	APG12; APG12L; FBR93; HAPG12
Summary	Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008]

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