Apg12 (ATG12) Rabbit Monoclonal Antibody [Clone ID: R08-2F4]

Specifications

Product Data
Clone Name	R08-2F4
Applications	WB
Recommend Dilution	WB: 1/1000-1/5000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human Apg12
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 15 kDa; Observed MW: 55 kDa
Gene Name	autophagy related 12
Database Link	Entrez Gene 9140 Human UniProt ID O94817
Background	Swiss-Prot Acc.O94817.Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
Synonyms	APG12; APG12-like; APG12L; FBR93; HAPG12
Reference Data

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