Human CD32 (FCGR2C) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FCGR2C
Locus ID	9103
Kit Components	GA106061G1, CD32 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106061G2, CD32 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106061G3, CD32 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001005410, NM_001005411, NM_001005412, NM_201563, NR_047648
Synonyms	CD32; CD32C; Fc fragment of IgG, low affinity IIc, receptor for; Fc fragment of IgG, low affinity IIc, receptor for (CD32); FcgammaRIIC; FCGR2B; FcRIIC; hFcRII-C
Summary	This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]

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