Human Huntingtin Associated Protein 1 (HAP1) activation kit by CRISPRa

CAT#: GA105986

HAP1 CRISPRa kit - CRISPR gene activation of human huntingtin associated protein 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal HAP1 Antibody
    • 100 ug

CNY 5,808.00


HAP1 (Myc-DDK-tagged)-Human huntingtin-associated protein 1 (HAP1), transcript variant 2
    • 10 ug

CNY 4,608.00


HAP1 Antibody - middle region
    • 50 ug

CNY 4,628.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol HAP1
Locus ID 9001
Kit Components

GA105986G1, Huntingtin Associated Protein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105986G2, Huntingtin Associated Protein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105986G3, Huntingtin Associated Protein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001079870, NM_001079871, NM_003949, NM_177977, NM_001367459, NM_001367460, NM_001367461, NM_001367462
Synonyms HAP2; hHLP1; HIP5; HLP
Summary Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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