Human TAX1BP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TAX1BP1
Locus ID	8887
Kit Components	GA105919G1, TAX1BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105919G2, TAX1BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105919G3, TAX1BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001079864, NM_001206901, NM_001206902, NM_006024, NM_001362794, NM_001362795
Synonyms	CALCOCO3; T6BP; TXBP151
Summary	This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

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