TAX1BP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 100-300 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 180-420 amino acids of human Tax1 (human T-cell leukemia virus type I) binding protein 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Tax1 binding protein 1
Database Link	NP_006015 Entrez Gene 52440 MouseEntrez Gene 246244 RatEntrez Gene 8887 Human UniProt ID Q86VP1
Background	This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3; and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[
Synonyms	CALCOCO3; T6BP; TXBP151
Reference Data
Protein Families	Druggable Genome

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