Human TRPM2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRPM2
Locus ID	7226
Kit Components	GA104983G1, TRPM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104983G2, TRPM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104983G3, TRPM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001188, NM_003307, NR_038257, NM_001320350, NM_001320351, NM_001320352
Synonyms	EREG1; KNP3; LTRPC2; MGC133383; NUDT9H; NUDT9L1; TRPC7
Summary	The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016]

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