Human MEK6 (MAP2K6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAP2K6
Locus ID	5608
Kit Components	GA103798G1, MEK6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103798G2, MEK6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103798G3, MEK6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001330450, NM_002758, NM_031988
Synonyms	MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3
Summary	This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]

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